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Page 1
Integrated CLL Scoring System, a New and Simple Index to Predict Time to Treatment and Overall Survival in Patients With Chronic Lymphocytic Leukemia.
Visentin A, Facco M, Frezzato F, Castelli M, Trimarco V, Martini V, Gattazzo C, Severin F, Chiodin G, Martines A, Bonaldi L, Gianesello I, Pagnin E, Boscaro E, Piazza F, Zambello R, Semenzato G, Trentin L. Visentin A, et al. Among authors: gattazzo c. Clin Lymphoma Myeloma Leuk. 2015 Oct;15(10):612-20.e1-5. doi: 10.1016/j.clml.2015.06.001. Epub 2015 Jun 20. Clin Lymphoma Myeloma Leuk. 2015. PMID: 26233718
Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival.
Trimarco V, Ave E, Facco M, Chiodin G, Frezzato F, Martini V, Gattazzo C, Lessi F, Giorgi CA, Visentin A, Castelli M, Severin F, Zambello R, Piazza F, Semenzato G, Trentin L. Trimarco V, et al. Among authors: gattazzo c. Oncotarget. 2015 Dec 8;6(39):42130-49. doi: 10.18632/oncotarget.6239. Oncotarget. 2015. PMID: 26517523 Free PMC article.
Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia.
Trentin L, Frasson M, Donella-Deana A, Frezzato F, Pagano MA, Tibaldi E, Gattazzo C, Zambello R, Semenzato G, Brunati AM. Trentin L, et al. Among authors: gattazzo c. Blood. 2008 Dec 1;112(12):4665-74. doi: 10.1182/blood-2008-02-139139. Epub 2008 Sep 2. Blood. 2008. PMID: 18768392 Free article.
HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen.
Frezzato F, Gattazzo C, Martini V, Trimarco V, Teramo A, Carraro S, Cabrelle A, Ave E, Facco M, Zambello R, Tibaldi E, Brunati AM, Semenzato G, Trentin L. Frezzato F, et al. Among authors: gattazzo c. PLoS One. 2012;7(6):e39902. doi: 10.1371/journal.pone.0039902. Epub 2012 Jun 29. PLoS One. 2012. PMID: 22768161 Free PMC article.
Intrinsic and extrinsic mechanisms contribute to maintain the JAK/STAT pathway aberrantly activated in T-type large granular lymphocyte leukemia.
Teramo A, Gattazzo C, Passeri F, Lico A, Tasca G, Cabrelle A, Martini V, Frezzato F, Trimarco V, Ave E, Boscaro E, Piazza F, Facco M, Trentin L, Semenzato G, Zambello R. Teramo A, et al. Among authors: gattazzo c. Blood. 2013 May 9;121(19):3843-54, S1. doi: 10.1182/blood-2012-07-441378. Epub 2013 Mar 20. Blood. 2013. PMID: 23515927 Free article.
Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia.
Gattazzo C, Martini V, Frezzato F, Trimarco V, Tibaldi E, Castelli M, Facco M, Zonta F, Brunati AM, Zambello R, Semenzato G, Trentin L. Gattazzo C, et al. Haematologica. 2014 Jun;99(6):1069-77. doi: 10.3324/haematol.2013.090183. Epub 2014 Feb 14. Haematologica. 2014. PMID: 24532043 Free PMC article.
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