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Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl.
Cortese-Krott MM, Kuhnle GG, Dyson A, Fernandez BO, Grman M, DuMond JF, Barrow MP, McLeod G, Nakagawa H, Ondrias K, Nagy P, King SB, Saavedra JE, Keefer LK, Singer M, Kelm M, Butler AR, Feelisch M. Cortese-Krott MM, et al. Among authors: saavedra je. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4651-60. doi: 10.1073/pnas.1509277112. Epub 2015 Jul 29. Proc Natl Acad Sci U S A. 2015. PMID: 26224837 Free PMC article.
Direct reaction of amides with nitric oxide to form diazeniumdiolates.
Holland RJ, Klose JR, Deschamps JR, Cao Z, Keefer LK, Saavedra JE. Holland RJ, et al. Among authors: saavedra je. J Org Chem. 2014 Oct 3;79(19):9389-93. doi: 10.1021/jo501670e. Epub 2014 Sep 22. J Org Chem. 2014. PMID: 25210948 Free PMC article.
HNO and NO release from a primary amine-based diazeniumdiolate as a function of pH.
Salmon DJ, Torres de Holding CL, Thomas L, Peterson KV, Goodman GP, Saavedra JE, Srinivasan A, Davies KM, Keefer LK, Miranda KM. Salmon DJ, et al. Among authors: saavedra je. Inorg Chem. 2011 Apr 18;50(8):3262-70. doi: 10.1021/ic101736e. Epub 2011 Mar 15. Inorg Chem. 2011. PMID: 21405089 Free PMC article.
166 results