Wang Y - Search Results

1

Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors.

Yang W, Li L, Wang Y, Wu X, Li T, Yang N, Su M, Sheng L, Zheng M, Zang Y, Li J, Liu H. Yang W, et al. Among authors: wang y. Bioorg Med Chem. 2015 Sep 1;23(17):5881-90. doi: 10.1016/j.bmc.2015.06.071. Epub 2015 Jul 4. Bioorg Med Chem. 2015. PMID: 26211462

2

Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer.

Zhu W, Chen H, Wang Y, Wang J, Peng X, Chen X, Gao Y, Li C, He Y, Ai J, Geng M, Zheng M, Liu H. Zhu W, et al. Among authors: wang j, wang y. J Med Chem. 2017 Jul 27;60(14):6018-6035. doi: 10.1021/acs.jmedchem.7b00076. Epub 2017 Jul 17. J Med Chem. 2017. PMID: 28714692

3

Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening.

Chen S, Wang Y, Zhou W, Li S, Peng J, Shi Z, Hu J, Liu YC, Ding H, Lin Y, Li L, Cheng S, Liu J, Lu T, Jiang H, Liu B, Zheng M, Luo C. Chen S, et al. Among authors: wang y. J Med Chem. 2014 Nov 13;57(21):9028-41. doi: 10.1021/jm501134e. Epub 2014 Nov 4. J Med Chem. 2014. PMID: 25333769

4

Discovery of Novel Disruptor of Silencing Telomeric 1-Like (DOT1L) Inhibitors using a Target-Specific Scoring Function for the (S)-Adenosyl-l-methionine (SAM)-Dependent Methyltransferase Family.

Wang Y, Li L, Zhang B, Xing J, Chen S, Wan W, Song Y, Jiang H, Jiang H, Luo C, Zheng M. Wang Y, et al. J Med Chem. 2017 Mar 9;60(5):2026-2036. doi: 10.1021/acs.jmedchem.6b01785. Epub 2017 Feb 21. J Med Chem. 2017. PMID: 28165739

5

Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.

Wang Y, Dai Y, Wu X, Li F, Liu B, Li C, Liu Q, Zhou Y, Wang B, Zhu M, Cui R, Tan X, Xiong Z, Liu J, Tan M, Xu Y, Geng M, Jiang H, Liu H, Ai J, Zheng M. Wang Y, et al. Among authors: wang b. J Med Chem. 2019 Aug 22;62(16):7473-7488. doi: 10.1021/acs.jmedchem.9b00510. Epub 2019 Aug 9. J Med Chem. 2019. PMID: 31335138

6

Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors.

Wu X, Dai M, Cui R, Wang Y, Li C, Peng X, Zhao J, Wang B, Dai Y, Feng D, Yang T, Jiang H, Geng M, Ai J, Zheng M, Liu H. Wu X, et al. Among authors: wang y, wang b. Acta Pharm Sin B. 2021 Mar;11(3):781-794. doi: 10.1016/j.apsb.2020.09.002. Epub 2020 Sep 7. Acta Pharm Sin B. 2021. PMID: 33777682 Free PMC article.

7

Identification of novel small molecules as inhibitors of hepatitis C virus by structure-based virtual screening.

Li J, Liu X, Li S, Wang Y, Zhou N, Luo C, Luo X, Zheng M, Jiang H, Chen K. Li J, et al. Among authors: wang y. Int J Mol Sci. 2013 Nov 20;14(11):22845-56. doi: 10.3390/ijms141122845. Int J Mol Sci. 2013. PMID: 24264035 Free PMC article.

8

Combinatorial Pharmacophore-Based 3D-QSAR Analysis and Virtual Screening of FGFR1 Inhibitors.

Zhou N, Xu Y, Liu X, Wang Y, Peng J, Luo X, Zheng M, Chen K, Jiang H. Zhou N, et al. Among authors: wang y. Int J Mol Sci. 2015 Jun 11;16(6):13407-26. doi: 10.3390/ijms160613407. Int J Mol Sci. 2015. PMID: 26110383 Free PMC article.

9

Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: A Combined Computational and Experimental Study.

Xu Y, Li L, Wang Y, Xing J, Zhou L, Zhong D, Luo X, Jiang H, Chen K, Zheng M, Deng P, Chen X. Xu Y, et al. Among authors: wang y. J Med Chem. 2017 Apr 13;60(7):2973-2982. doi: 10.1021/acs.jmedchem.7b00019. Epub 2017 Mar 16. J Med Chem. 2017. PMID: 28263602

10

Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.

Ye Y, Zhang B, Mao R, Zhang C, Wang Y, Xing J, Liu YC, Luo X, Ding H, Yang Y, Zhou B, Jiang H, Chen K, Luo C, Zheng M. Ye Y, et al. Among authors: wang y. Org Biomol Chem. 2017 May 3;15(17):3648-3661. doi: 10.1039/c7ob00070g. Org Biomol Chem. 2017. PMID: 28397890

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