Clarke AR - Search Results

1

Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer.

Raja M, Zverev M, Seipel K, Williams GT, Clarke AR, Shaw PH. Raja M, et al. Among authors: clarke ar. Mol Cancer Ther. 2015 Oct;14(10):2175-86. doi: 10.1158/1535-7163.MCT-15-0223. Epub 2015 Jul 23. Mol Cancer Ther. 2015. PMID: 26206338

2

RNA Interference Using c-Myc-Conjugated Nanoparticles Suppresses Breast and Colorectal Cancer Models.

Tangudu NK, Verma VK, Clemons TD, Beevi SS, Hay T, Mahidhara G, Raja M, Nair RA, Alexander LE, Patel AB, Jose J, Smith NM, Zdyrko B, Bourdoncle A, Luzinov I, Iyer KS, Clarke AR, Dinesh Kumar L. Tangudu NK, et al. Among authors: clarke ar. Mol Cancer Ther. 2015 May;14(5):1259-69. doi: 10.1158/1535-7163.MCT-14-0970. Epub 2015 Feb 18. Mol Cancer Ther. 2015. PMID: 25695957 Free article.

3

Murine models of intestinal cancer: recent advances.

Shaw P, Clarke AR. Shaw P, et al. Among authors: clarke ar. DNA Repair (Amst). 2007 Oct 1;6(10):1403-12. doi: 10.1016/j.dnarep.2007.02.022. Epub 2007 Mar 21. DNA Repair (Amst). 2007. PMID: 17376749 Review.

4

PTEN loss and KRAS activation cooperate in murine biliary tract malignancies.

Marsh V, Davies EJ, Williams GT, Clarke AR. Marsh V, et al. Among authors: clarke ar. J Pathol. 2013 Jun;230(2):165-73. doi: 10.1002/path.4189. J Pathol. 2013. PMID: 23483557

5

PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.

Davies EJ, Marsh Durban V, Meniel V, Williams GT, Clarke AR. Davies EJ, et al. Among authors: clarke ar. J Pathol. 2014 May;233(1):27-38. doi: 10.1002/path.4312. Epub 2014 Jan 23. J Pathol. 2014. PMID: 24293351

6

Dual inhibition of epidermal growth factor and insulin-like 1 growth factor receptors reduce intestinal adenoma burden in the Apc(min/+) mouse.

Shaw PH, Maughan TS, Clarke AR. Shaw PH, et al. Among authors: clarke ar. Br J Cancer. 2011 Aug 23;105(5):649-57. doi: 10.1038/bjc.2011.291. Epub 2011 Aug 2. Br J Cancer. 2011. PMID: 21811251 Free PMC article.

7

Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation.

Marsh V, Winton DJ, Williams GT, Dubois N, Trumpp A, Sansom OJ, Clarke AR. Marsh V, et al. Among authors: clarke ar. Nat Genet. 2008 Dec;40(12):1436-44. doi: 10.1038/ng.256. Epub 2008 Nov 16. Nat Genet. 2008. PMID: 19011632

8

3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.

Badder LM, Hollins AJ, Herpers B, Yan K, Ewan KB, Thomas M, Shone JR, Badder DA, Naven M, Ashelford KE, Hargest R, Clarke AR, Esdar C, Buchstaller HP, Treherne JM, Boj S, Ramezanpour B, Wienke D, Price LS, Shaw PH, Dale TC. Badder LM, et al. Among authors: clarke ar. PLoS One. 2020 Aug 18;15(8):e0235319. doi: 10.1371/journal.pone.0235319. eCollection 2020. PLoS One. 2020. PMID: 32810173 Free PMC article.

9

Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency.

Greenow KR, Clarke AR, Williams GT, Jones R. Greenow KR, et al. Among authors: clarke ar. Oncogene. 2014 Jul 31;33(31):4089-96. doi: 10.1038/onc.2013.371. Epub 2013 Sep 16. Oncogene. 2014. PMID: 24037525

10

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

Daly CS, Shaw P, Ordonez LD, Williams GT, Quist J, Grigoriadis A, Van Es JH, Clevers H, Clarke AR, Reed KR. Daly CS, et al. Among authors: clarke ar. Oncogene. 2017 Mar 30;36(13):1793-1803. doi: 10.1038/onc.2016.342. Epub 2016 Oct 3. Oncogene. 2017. PMID: 27694902 Free PMC article.

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