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In vitro and in vivo activities of PD 0305970 and PD 0326448, new bacterial gyrase/topoisomerase inhibitors with potent antibacterial activities versus multidrug-resistant gram-positive and fastidious organism groups.
Huband MD, Cohen MA, Zurack M, Hanna DL, Skerlos LA, Sulavik MC, Gibson GW, Gage JW, Ellsworth E, Stier MA, Gracheck SJ. Huband MD, et al. Antimicrob Agents Chemother. 2007 Apr;51(4):1191-201. doi: 10.1128/AAC.01321-06. Epub 2007 Jan 29. Antimicrob Agents Chemother. 2007. PMID: 17261623 Free PMC article.
In vitro antibacterial activity of CE-156811, a novel analog derived from hygromycin A.
Stone GG, Girard D, Finegan S, Duignan J, Schafer J, Maloney M, Zaniewski RP, Brickner SJ, Wade SK, Le PT, Huband MD. Stone GG, et al. Among authors: huband md. Antimicrob Agents Chemother. 2008 Jul;52(7):2663-6. doi: 10.1128/AAC.01326-07. Epub 2008 Apr 21. Antimicrob Agents Chemother. 2008. PMID: 18426902 Free PMC article.
High in vitro activity of the novel spiropyrimidinetrione AZD0914, a DNA gyrase inhibitor, against multidrug-resistant Neisseria gonorrhoeae isolates suggests a new effective option for oral treatment of gonorrhea.
Jacobsson S, Golparian D, Alm RA, Huband M, Mueller J, Jensen JS, Ohnishi M, Unemo M. Jacobsson S, et al. Antimicrob Agents Chemother. 2014 Sep;58(9):5585-8. doi: 10.1128/AAC.03090-14. Epub 2014 Jun 30. Antimicrob Agents Chemother. 2014. PMID: 24982070 Free PMC article.
In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria.
Huband MD, Bradford PA, Otterson LG, Basarab GS, Kutschke AC, Giacobbe RA, Patey SA, Alm RA, Johnstone MR, Potter ME, Miller PF, Mueller JP. Huband MD, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):467-74. doi: 10.1128/AAC.04124-14. Epub 2014 Nov 10. Antimicrob Agents Chemother. 2015. PMID: 25385112 Free PMC article.
109 results