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The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming.
Phan L, Chou PC, Velazquez-Torres G, Samudio I, Parreno K, Huang Y, Tseng C, Vu T, Gully C, Su CH, Wang E, Chen J, Choi HH, Fuentes-Mattei E, Shin JH, Shiang C, Grabiner B, Blonska M, Skerl S, Shao Y, Cody D, Delacerda J, Kingsley C, Webb D, Carlock C, Zhou Z, Hsieh YC, Lee J, Elliott A, Ramirez M, Bankson J, Hazle J, Wang Y, Li L, Weng S, Rizk N, Wen YY, Lin X, Wang H, Wang H, Zhang A, Xia X, Wu Y, Habra M, Yang W, Pusztai L, Yeung SC, Lee MH. Phan L, et al. Among authors: lee mh, lee j. Nat Commun. 2015 Jul 16;6:7530. doi: 10.1038/ncomms8530. Nat Commun. 2015. PMID: 26179207 Free PMC article.
Roles for CSN5 in control of p53/MDM2 activities.
Zhang XC, Chen J, Su CH, Yang HY, Lee MH. Zhang XC, et al. Among authors: lee mh. J Cell Biochem. 2008 Mar 1;103(4):1219-30. doi: 10.1002/jcb.21504. J Cell Biochem. 2008. PMID: 17879958
Pim-1 plays a pivotal role in hypoxia-induced chemoresistance.
Chen J, Kobayashi M, Darmanin S, Qiao Y, Gully C, Zhao R, Yeung SC, Lee MH. Chen J, et al. Among authors: lee mh. Oncogene. 2009 Jul 16;28(28):2581-92. doi: 10.1038/onc.2009.124. Epub 2009 Jun 1. Oncogene. 2009. PMID: 19483729 Free PMC article.
Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation.
Chen J, Kobayashi M, Darmanin S, Qiao Y, Gully C, Zhao R, Kondo S, Wang H, Wang H, Yeung SC, Lee MH. Chen J, et al. Among authors: lee mh. Am J Pathol. 2009 Jul;175(1):400-11. doi: 10.2353/ajpath.2009.080972. Epub 2009 Jun 15. Am J Pathol. 2009. PMID: 19528349 Free PMC article.
Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.
Zhao R, Yeung SC, Chen J, Iwakuma T, Su CH, Chen B, Qu C, Zhang F, Chen YT, Lin YL, Lee DF, Jin F, Zhu R, Shaikenov T, Sarbassov D, Sahin A, Wang H, Wang H, Lai CC, Tsai FJ, Lozano G, Lee MH. Zhao R, et al. Among authors: lee mh, lee df. J Clin Invest. 2011 Mar;121(3):851-65. doi: 10.1172/JCI44111. Epub 2011 Feb 7. J Clin Invest. 2011. PMID: 21317535 Free PMC article.
5,345 results