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The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma.
Wagener R, Aukema SM, Schlesner M, Haake A, Burkhardt B, Claviez A, Drexler HG, Hummel M, Kreuz M, Loeffler M, Rosolowski M, López C, Möller P, Richter J, Rohde M, Betts MJ, Russell RB, Bernhart SH, Hoffmann S, Rosenstiel P, Schilhabel M, Szczepanowski M, Trümper L, Klapper W, Siebert R; ICGC MMML-Seq-Project; "Molecular Mechanisms in Malignant Lymphomas" Network Project of the Deutsche Krebshilfe. Wagener R, et al. Among authors: betts mj. Genes Chromosomes Cancer. 2015 Sep;54(9):555-64. doi: 10.1002/gcc.22268. Epub 2015 Jul 14. Genes Chromosomes Cancer. 2015. PMID: 26173642
Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia.
Bergmann AK, Schneppenheim S, Seifert M, Betts MJ, Haake A, Lopez C, Maria Murga Penas E, Vater I, Jayne S, Dyer MJ, Schrappe M, Dührsen U, Ammerpohl O, Russell RB, Küppers R, Dürig J, Siebert R. Bergmann AK, et al. Among authors: betts mj. Genes Chromosomes Cancer. 2014 Apr;53(4):309-16. doi: 10.1002/gcc.22141. Epub 2014 Jan 21. Genes Chromosomes Cancer. 2014. PMID: 24446122
Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols.
Rohde M, Richter J, Schlesner M, Betts MJ, Claviez A, Bonn BR, Zimmermann M, Damm-Welk C, Russell RB, Borkhardt A, Eils R, Hoell JI, Szczepanowski M, Oschlies I, Klapper W, Burkhardt B, Siebert R; German ICGC MMML-Seq-Project; NHL-BFM Study Group. Rohde M, et al. Among authors: betts mj. Genes Chromosomes Cancer. 2014 Nov;53(11):911-6. doi: 10.1002/gcc.22202. Epub 2014 Jul 8. Genes Chromosomes Cancer. 2014. PMID: 25044415
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control.
Kretzmer H, Bernhart SH, Wang W, Haake A, Weniger MA, Bergmann AK, Betts MJ, Carrillo-de-Santa-Pau E, Doose G, Gutwein J, Richter J, Hovestadt V, Huang B, Rico D, Jühling F, Kolarova J, Lu Q, Otto C, Wagener R, Arnolds J, Burkhardt B, Claviez A, Drexler HG, Eberth S, Eils R, Flicek P, Haas S, Humme M, Karsch D, Kerstens HHD, Klapper W, Kreuz M, Lawerenz C, Lenzek D, Loeffler M, López C, MacLeod RAF, Martens JHA, Kulis M, Martín-Subero JI, Möller P, Nage I, Picelli S, Vater I, Rohde M, Rosenstiel P, Rosolowski M, Russell RB, Schilhabel M, Schlesner M, Stadler PF, Szczepanowski M, Trümper L, Stunnenberg HG, Küppers R, Ammerpohl O, Lichter P, Siebert R, Hoffmann S, Radlwimmer B. Kretzmer H, et al. Among authors: betts mj. Nat Genet. 2015 Nov;47(11):1316-1325. doi: 10.1038/ng.3413. Epub 2015 Oct 5. Nat Genet. 2015. PMID: 26437030 Free PMC article.
Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia.
López C, Bergmann AK, Paul U, Murga Penas EM, Nagel I, Betts MJ, Johansson P, Ritgen M, Baumann T, Aymerich M, Jayne S, Russell RB, Campo E, Dyer MJ, Dürig J, Siebert R. López C, et al. Among authors: betts mj. Br J Haematol. 2016 Apr;173(2):265-73. doi: 10.1111/bjh.13952. Epub 2016 Feb 25. Br J Haematol. 2016. PMID: 26917488 Free article.
The hard cell: from proteomics to a whole cell model.
Betts MJ, Russell RB. Betts MJ, et al. FEBS Lett. 2007 Jun 19;581(15):2870-6. doi: 10.1016/j.febslet.2007.05.062. Epub 2007 May 30. FEBS Lett. 2007. PMID: 17555749 Free article. Review.
A more structured metabolome.
Betts MJ, Russell RB. Betts MJ, et al. Nat Struct Mol Biol. 2009 Nov;16(11):1125-6. doi: 10.1038/nsmb1109-1125. Nat Struct Mol Biol. 2009. PMID: 19888310 No abstract available.
89 results