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Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues.
Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Lu M, et al. Among authors: bandyopadhyay g. J Biol Chem. 2013 Apr 12;288(15):10722-35. doi: 10.1074/jbc.M112.443606. Epub 2013 Mar 1. J Biol Chem. 2013. PMID: 23457303 Free PMC article.
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity.
Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM. Yoshizaki T, et al. Among authors: bandyopadhyay g. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E419-28. doi: 10.1152/ajpendo.00417.2009. Epub 2009 Dec 8. Am J Physiol Endocrinol Metab. 2010. PMID: 19996381 Free PMC article.
Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes.
Saberi M, Bjelica D, Schenk S, Imamura T, Bandyopadhyay G, Li P, Jadhar V, Vargeese C, Wang W, Bowman K, Zhang Y, Polisky B, Olefsky JM. Saberi M, et al. Among authors: bandyopadhyay g. Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1137-46. doi: 10.1152/ajpendo.00158.2009. Epub 2009 Aug 25. Am J Physiol Endocrinol Metab. 2009. PMID: 19706791 Free PMC article.
172 results