Loft A - Search Results

1

Acute TNF-induced repression of cell identity genes is mediated by NFκB-directed redistribution of cofactors from super-enhancers.

Schmidt SF, Larsen BD, Loft A, Nielsen R, Madsen JG, Mandrup S. Schmidt SF, et al. Among authors: loft a. Genome Res. 2015 Sep;25(9):1281-94. doi: 10.1101/gr.188300.114. Epub 2015 Jun 25. Genome Res. 2015. PMID: 26113076 Free PMC article.

2

Transcription factor cooperativity in early adipogenic hotspots and super-enhancers.

Siersbæk R, Rabiee A, Nielsen R, Sidoli S, Traynor S, Loft A, Poulsen LC, Rogowska-Wrzesinska A, Jensen ON, Mandrup S. Siersbæk R, et al. Among authors: loft a. Cell Rep. 2014 Jun 12;7(5):1443-1455. doi: 10.1016/j.celrep.2014.04.042. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857652 Free article.

3

Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers.

Loft A, Forss I, Siersbæk MS, Schmidt SF, Larsen AS, Madsen JG, Pisani DF, Nielsen R, Aagaard MM, Mathison A, Neville MJ, Urrutia R, Karpe F, Amri EZ, Mandrup S. Loft A, et al. Genes Dev. 2015 Jan 1;29(1):7-22. doi: 10.1101/gad.250829.114. Epub 2014 Dec 12. Genes Dev. 2015. PMID: 25504365 Free PMC article.

4

Modulating the Genomic Programming of Adipocytes.

Loft A, Schmidt SF, Mandrup S. Loft A, et al. Cold Spring Harb Symp Quant Biol. 2015;80:239-48. doi: 10.1101/sqb.2015.80.027516. Epub 2015 Oct 2. Cold Spring Harb Symp Quant Biol. 2015. PMID: 26432526 Review.

5

Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells.

Schmidt SF, Madsen JG, Frafjord KØ, Poulsen Ll, Salö S, Boergesen M, Loft A, Larsen BD, Madsen MS, Holst JJ, Maechler P, Dalgaard LT, Mandrup S. Schmidt SF, et al. Among authors: loft a. Cell Rep. 2016 Aug 30;16(9):2359-72. doi: 10.1016/j.celrep.2016.07.063. Epub 2016 Aug 18. Cell Rep. 2016. PMID: 27545881 Free article.

6

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation.

Brier AB, Loft A, Madsen JGS, Rosengren T, Nielsen R, Schmidt SF, Liu Z, Yan Q, Gronemeyer H, Mandrup S. Brier AB, et al. Among authors: loft a. Nucleic Acids Res. 2017 Feb 28;45(4):1743-1759. doi: 10.1093/nar/gkw1156. Nucleic Acids Res. 2017. PMID: 27899593 Free PMC article.

7

Analysis of Enhancers and Transcriptional Networks in Thermogenic Adipocytes.

Loft A, Andersen MW, Madsen JGS, Mandrup S. Loft A, et al. Methods Mol Biol. 2022;2448:155-175. doi: 10.1007/978-1-0716-2087-8_11. Methods Mol Biol. 2022. PMID: 35167097

8

Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.

Siersbæk R, Nielsen R, John S, Sung MH, Baek S, Loft A, Hager GL, Mandrup S. Siersbæk R, et al. Among authors: loft a. EMBO J. 2011 Apr 20;30(8):1459-72. doi: 10.1038/emboj.2011.65. Epub 2011 Mar 22. EMBO J. 2011. PMID: 21427703 Free PMC article.

9

Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression.

Siersbæk MS, Loft A, Aagaard MM, Nielsen R, Schmidt SF, Petrovic N, Nedergaard J, Mandrup S. Siersbæk MS, et al. Among authors: loft a. Mol Cell Biol. 2012 Sep;32(17):3452-63. doi: 10.1128/MCB.00526-12. Epub 2012 Jun 25. Mol Cell Biol. 2012. PMID: 22733994 Free PMC article.

10

iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data.

Madsen JG, Schmidt SF, Larsen BD, Loft A, Nielsen R, Mandrup S. Madsen JG, et al. Among authors: loft a. Nucleic Acids Res. 2015 Mar 31;43(6):e40. doi: 10.1093/nar/gku1365. Epub 2015 Jan 6. Nucleic Acids Res. 2015. PMID: 25564527 Free PMC article.

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