McPate M - Search Results

1

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.

Carson C, Raman P, Tullai J, Xu L, Henault M, Thomas E, Yeola S, Lao J, McPate M, Verkuyl JM, Marsh G, Sarber J, Amaral A, Bailey S, Lubicka D, Pham H, Miranda N, Ding J, Tang HM, Ju H, Tranter P, Ji N, Krastel P, Jain RK, Schumacher AM, Loureiro JJ, George E, Berellini G, Ross NT, Bushell SM, Erdemli G, Solomon JM. Carson C, et al. Among authors: mcpate m. PLoS One. 2015 Jun 22;10(6):e0127498. doi: 10.1371/journal.pone.0127498. eCollection 2015. PLoS One. 2015. PMID: 26098886 Free PMC article.

2

The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7.

McPate M, Bhalay G, Beckett M, Fairbrother S, Gosling M, Groot-Kormelink PJ, Lane R, Kent T, Van Diepen MT, Tranter P, Verkuyl JM. McPate M, et al. Assay Drug Dev Technol. 2014 Jun;12(5):282-92. doi: 10.1089/adt.2014.574. Epub 2014 Jun 6. Assay Drug Dev Technol. 2014. PMID: 24906109

3

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease.

Miller AT, Dahlberg C, Sandberg ML, Wen BG, Beisner DR, Hoerter JA, Parker A, Schmedt C, Stinson M, Avis J, Cienfuegos C, McPate M, Tranter P, Gosling M, Groot-Kormelink PJ, Dawson J, Pan S, Tian SS, Seidel HM, Cooke MP. Miller AT, et al. Among authors: mcpate m. PLoS One. 2015 Jun 29;10(6):e0131071. doi: 10.1371/journal.pone.0131071. eCollection 2015. PLoS One. 2015. PMID: 26121493 Free PMC article.

4

Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome.

El Harchi A, McPate MJ, Zhang Yh, Zhang H, Hancox JC. El Harchi A, et al. Among authors: mcpate mj. J Mol Cell Cardiol. 2009 Nov;47(5):743-7. doi: 10.1016/j.yjmcc.2009.02.027. Epub 2009 Mar 10. J Mol Cell Cardiol. 2009. PMID: 19285083 Free PMC article.

5

Action potential clamp and mefloquine sensitivity of recombinant 'I KS' channels incorporating the V307L KCNQ1 mutation.

El Harchi A, McPate MJ, Zhang YH, Zhang H, Hancox JC. El Harchi A, et al. Among authors: mcpate mj. J Physiol Pharmacol. 2010 Apr;61(2):123-31. J Physiol Pharmacol. 2010. PMID: 20436212 Free article.

6

The hERG potassium channel and hERG screening for drug-induced torsades de pointes.

Hancox JC, McPate MJ, El Harchi A, Zhang YH. Hancox JC, et al. Pharmacol Ther. 2008 Aug;119(2):118-32. doi: 10.1016/j.pharmthera.2008.05.009. Epub 2008 Jun 18. Pharmacol Ther. 2008. PMID: 18616963 Review.

7

Acidosis impairs the protective role of hERG K(+) channels against premature stimulation.

Du CY, Adeniran I, Cheng H, Zhang YH, El Harchi A, McPate MJ, Zhang H, Orchard CH, Hancox JC. Du CY, et al. Among authors: mcpate mj. J Cardiovasc Electrophysiol. 2010 Oct;21(10):1160-9. doi: 10.1111/j.1540-8167.2010.01772.x. J Cardiovasc Electrophysiol. 2010. PMID: 20455975

8

Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin.

Duncan RS, McPate MJ, Ridley JM, Gao Z, James AF, Leishman DJ, Leaney JL, Witchel HJ, Hancox JC. Duncan RS, et al. Among authors: mcpate mj. Biochem Pharmacol. 2007 Aug 1;74(3):425-37. doi: 10.1016/j.bcp.2007.04.024. Epub 2007 May 3. Biochem Pharmacol. 2007. PMID: 17560554 Free PMC article.

9

Pharmacology of the short QT syndrome N588K-hERG K+ channel mutation: differential impact on selected class I and class III antiarrhythmic drugs.

McPate MJ, Duncan RS, Hancox JC, Witchel HJ. McPate MJ, et al. Br J Pharmacol. 2008 Nov;155(6):957-66. doi: 10.1038/bjp.2008.325. Epub 2008 Aug 25. Br J Pharmacol. 2008. PMID: 18724381 Free PMC article.

10

Comparative effects of the short QT N588K mutation at 37 degrees C on hERG K+ channel current during ventricular, Purkinje fibre and atrial action potentials: an action potential clamp study.

McPate MJ, Zhang H, Adeniran I, Cordeiro JM, Witchel HJ, Hancox JC. McPate MJ, et al. J Physiol Pharmacol. 2009 Mar;60(1):23-41. J Physiol Pharmacol. 2009. PMID: 19439805 Free article.

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