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C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease.
De Vos A, Jacobs D, Struyfs H, Fransen E, Andersson K, Portelius E, Andreasson U, De Surgeloose D, Hernalsteen D, Sleegers K, Robberecht C, Van Broeckhoven C, Zetterberg H, Blennow K, Engelborghs S, Vanmechelen E. De Vos A, et al. Among authors: jacobs d. Alzheimers Dement. 2015 Dec;11(12):1461-1469. doi: 10.1016/j.jalz.2015.05.012. Epub 2015 Jun 16. Alzheimers Dement. 2015. PMID: 26092348 Free article.
Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnostics.
Rosseels J, Van den Brande J, Violet M, Jacobs D, Grognet P, Lopez J, Huvent I, Caldara M, Swinnen E, Papegaey A, Caillierez R, Buée-Scherrer V, Engelborghs S, Lippens G, Colin M, Buée L, Galas MC, Vanmechelen E, Winderickx J. Rosseels J, et al. Among authors: jacobs d. J Biol Chem. 2015 Feb 13;290(7):4059-74. doi: 10.1074/jbc.M114.627919. Epub 2014 Dec 24. J Biol Chem. 2015. PMID: 25540200 Free PMC article.
Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer's disease.
Galasko D, Xiao M, Xu D, Smirnov D, Salmon DP, Dewit N, Vanbrabant J, Jacobs D, Vanderstichele H, Vanmechelen E; Alzheimer's Disease Neuroimaging Initiative (ADNI); Worley P. Galasko D, et al. Among authors: jacobs d. Alzheimers Dement (N Y). 2019 Dec 9;5:871-882. doi: 10.1016/j.trci.2019.11.002. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31853477 Free PMC article.
A Novel Neurofilament Light Chain ELISA Validated in Patients with Alzheimer's Disease, Frontotemporal Dementia, and Subjective Cognitive Decline, and the Evaluation of Candidate Proteins for Immunoassay Calibration.
Das S, Dewit N, Jacobs D, Pijnenburg YAL, In 't Veld SGJG, Coppens S, Quaglia M, Hirtz C, Teunissen CE, Vanmechelen E. Das S, et al. Among authors: jacobs d. Int J Mol Sci. 2022 Jun 29;23(13):7221. doi: 10.3390/ijms23137221. Int J Mol Sci. 2022. PMID: 35806226 Free PMC article.
A Combination of Neurofilament Light, Glial Fibrillary Acidic Protein, and Neuronal Pentraxin-2 Discriminates Between Frontotemporal Dementia and Other Dementias.
Bolsewig K, Hok-A-Hin YS, Sepe FN, Boonkamp L, Jacobs D, Bellomo G, Paoletti FP, Vanmechelen E, Teunissen CE, Parnetti L, Willemse EAJ. Bolsewig K, et al. Among authors: jacobs d. J Alzheimers Dis. 2022;90(1):363-380. doi: 10.3233/JAD-220318. J Alzheimers Dis. 2022. PMID: 36120776 Free PMC article.
3,126 results