Joyce JA - Search Results

1

Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells.

Sobotič B, Vizovišek M, Vidmar R, Van Damme P, Gocheva V, Joyce JA, Gevaert K, Turk V, Turk B, Fonović M. Sobotič B, et al. Among authors: joyce ja. Mol Cell Proteomics. 2015 Aug;14(8):2213-28. doi: 10.1074/mcp.M114.044628. Epub 2015 Jun 16. Mol Cell Proteomics. 2015. PMID: 26081835 Free PMC article.

2

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.

Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA. Gocheva V, et al. Among authors: joyce ja. Genes Dev. 2006 Mar 1;20(5):543-56. doi: 10.1101/gad.1407406. Epub 2006 Feb 15. Genes Dev. 2006. PMID: 16481467 Free PMC article.

3

Cysteine cathepsins and the cutting edge of cancer invasion.

Gocheva V, Joyce JA. Gocheva V, et al. Among authors: joyce ja. Cell Cycle. 2007 Jan 1;6(1):60-4. doi: 10.4161/cc.6.1.3669. Epub 2007 Jan 6. Cell Cycle. 2007. PMID: 17245112 Review.

4

Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases.

Sadaghiani AM, Verhelst SH, Gocheva V, Hill K, Majerova E, Stinson S, Joyce JA, Bogyo M. Sadaghiani AM, et al. Among authors: joyce ja. Chem Biol. 2007 May;14(5):499-511. doi: 10.1016/j.chembiol.2007.03.010. Chem Biol. 2007. PMID: 17524981

5

Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer.

Bell-McGuinn KM, Garfall AL, Bogyo M, Hanahan D, Joyce JA. Bell-McGuinn KM, et al. Among authors: joyce ja. Cancer Res. 2007 Aug 1;67(15):7378-85. doi: 10.1158/0008-5472.CAN-07-0602. Cancer Res. 2007. PMID: 17671208

6

Cysteine cathepsin proteases as pharmacological targets in cancer.

Palermo C, Joyce JA. Palermo C, et al. Among authors: joyce ja. Trends Pharmacol Sci. 2008 Jan;29(1):22-8. doi: 10.1016/j.tips.2007.10.011. Epub 2007 Nov 26. Trends Pharmacol Sci. 2008. PMID: 18037508 Review.

7

VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation.

Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. Chang SH, et al. Among authors: joyce j. Cancer Res. 2009 May 15;69(10):4537-44. doi: 10.1158/0008-5472.CAN-08-4539. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435903 Free PMC article.

8

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.

Gocheva V, Wang HW, Gadea BB, Shree T, Hunter KE, Garfall AL, Berman T, Joyce JA. Gocheva V, et al. Among authors: joyce ja. Genes Dev. 2010 Feb 1;24(3):241-55. doi: 10.1101/gad.1874010. Epub 2010 Jan 15. Genes Dev. 2010. PMID: 20080943 Free PMC article.

9

Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.

Elie BT, Gocheva V, Shree T, Dalrymple SA, Holsinger LJ, Joyce JA. Elie BT, et al. Among authors: joyce ja. Biochimie. 2010 Nov;92(11):1618-24. doi: 10.1016/j.biochi.2010.04.023. Epub 2010 May 4. Biochimie. 2010. PMID: 20447439 Free PMC article.

10

Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer.

Gocheva V, Chen X, Peters C, Reinheckel T, Joyce JA. Gocheva V, et al. Among authors: joyce ja. Biol Chem. 2010 Aug;391(8):937-45. doi: 10.1515/BC.2010.080. Biol Chem. 2010. PMID: 20731543 Free PMC article.

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