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Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors.
Maione S, Bisogno T, de Novellis V, Palazzo E, Cristino L, Valenti M, Petrosino S, Guglielmotti V, Rossi F, Di Marzo V. Maione S, et al. Among authors: cristino l. J Pharmacol Exp Ther. 2006 Mar;316(3):969-82. doi: 10.1124/jpet.105.093286. Epub 2005 Nov 11. J Pharmacol Exp Ther. 2006. PMID: 16284279
Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception.
Marabese I, Rossi F, Palazzo E, de Novellis V, Starowicz K, Cristino L, Vita D, Gatta L, Guida F, Di Marzo V, Rossi F, Maione S. Marabese I, et al. Among authors: cristino l. J Neurophysiol. 2007 Jul;98(1):43-53. doi: 10.1152/jn.00356.2007. Epub 2007 May 16. J Neurophysiol. 2007. PMID: 17507496 Free article.
Why endocannabinoids are not all alike.
Di Marzo V, Cristino L. Di Marzo V, et al. Among authors: cristino l. Nat Neurosci. 2008 Feb;11(2):124-6. doi: 10.1038/nn0208-124. Nat Neurosci. 2008. PMID: 18227793 No abstract available.
92 results