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miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.
Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA. Guda S, et al. Among authors: gregory ri. Mol Ther. 2015 Sep;23(9):1465-74. doi: 10.1038/mt.2015.113. Epub 2015 Jun 17. Mol Ther. 2015. PMID: 26080908 Free PMC article.
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.
Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Piskounova E, et al. Among authors: gregory ri. Cell. 2011 Nov 23;147(5):1066-79. doi: 10.1016/j.cell.2011.10.039. Cell. 2011. PMID: 22118463 Free PMC article.
How does Lin28 let-7 control development and disease?
Thornton JE, Gregory RI. Thornton JE, et al. Among authors: gregory ri. Trends Cell Biol. 2012 Sep;22(9):474-82. doi: 10.1016/j.tcb.2012.06.001. Epub 2012 Jul 9. Trends Cell Biol. 2012. PMID: 22784697 Free PMC article. Review.
Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4).
Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI. Thornton JE, et al. Among authors: gregory ri. Nucleic Acids Res. 2014 Oct;42(18):11777-91. doi: 10.1093/nar/gku805. Epub 2014 Sep 15. Nucleic Acids Res. 2014. PMID: 25223788 Free PMC article.
PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells.
Das PP, Hendrix DA, Apostolou E, Buchner AH, Canver MC, Beyaz S, Ljuboja D, Kuintzle R, Kim W, Karnik R, Shao Z, Xie H, Xu J, De Los Angeles A, Zhang Y, Choe J, Jun DL, Shen X, Gregory RI, Daley GQ, Meissner A, Kellis M, Hochedlinger K, Kim J, Orkin SH. Das PP, et al. Among authors: gregory ri. Cell Rep. 2015 Sep 1;12(9):1456-70. doi: 10.1016/j.celrep.2015.07.053. Epub 2015 Aug 20. Cell Rep. 2015. PMID: 26299972 Free PMC article.
88 results