Howe SJ - Search Results

1

Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates.

Mattar CN, Wong AM, Hoefer K, Alonso-Ferrero ME, Buckley SM, Howe SJ, Cooper JD, Waddington SN, Chan JK, Rahim AA. Mattar CN, et al. Among authors: howe sj. FASEB J. 2015 Sep;29(9):3876-88. doi: 10.1096/fj.14-269092. Epub 2015 Jun 10. FASEB J. 2015. PMID: 26062602 Free PMC article.

2

Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors.

Rahim AA, Wong AM, Howe SJ, Buckley SM, Acosta-Saltos AD, Elston KE, Ward NJ, Philpott NJ, Cooper JD, Anderson PN, Waddington SN, Thrasher AJ, Raivich G. Rahim AA, et al. Among authors: howe sj. Gene Ther. 2009 Apr;16(4):509-20. doi: 10.1038/gt.2008.186. Epub 2009 Jan 22. Gene Ther. 2009. PMID: 19158847

3

Perinatal gene transfer to the liver.

McKay TR, Rahim AA, Buckley SM, Ward NJ, Chan JK, Howe SJ, Waddington SN. McKay TR, et al. Among authors: howe sj. Curr Pharm Des. 2011;17(24):2528-41. doi: 10.2174/138161211797247541. Curr Pharm Des. 2011. PMID: 21774770 Free PMC article. Review.

4

Evidence for contribution of CD4+ CD25+ regulatory T cells in maintaining immune tolerance to human factor IX following perinatal adenovirus vector delivery.

Nivsarkar MS, Buckley SM, Parker AL, Perocheau D, McKay TR, Rahim AA, Howe SJ, Waddington SN. Nivsarkar MS, et al. Among authors: howe sj. J Immunol Res. 2015;2015:397879. doi: 10.1155/2015/397879. Epub 2015 Jan 31. J Immunol Res. 2015. PMID: 25759840 Free PMC article.

5

In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters.

Buckley SM, Delhove JM, Perocheau DP, Karda R, Rahim AA, Howe SJ, Ward NJ, Birrell MA, Belvisi MG, Arbuthnot P, Johnson MR, Waddington SN, McKay TR. Buckley SM, et al. Among authors: howe sj. Sci Rep. 2015 Jul 3;5:11842. doi: 10.1038/srep11842. Sci Rep. 2015. PMID: 26138224 Free PMC article.

6

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.

Vink CA, Counsell JR, Perocheau DP, Karda R, Buckley SMK, Brugman MH, Galla M, Schambach A, McKay TR, Waddington SN, Howe SJ. Vink CA, et al. Among authors: howe sj. Mol Ther. 2017 Aug 2;25(8):1790-1804. doi: 10.1016/j.ymthe.2017.04.028. Epub 2017 May 24. Mol Ther. 2017. PMID: 28550974 Free PMC article.

7

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors.

Alonso-Ferrero ME, van Til NP, Bartolovic K, Mata MF, Wagemaker G, Moulding D, Williams DA, Kinnon C, Waddington SN, Milsom MD, Howe SJ. Alonso-Ferrero ME, et al. Among authors: howe sj. Exp Hematol. 2018 Jan;57:21-29. doi: 10.1016/j.exphem.2017.09.003. Epub 2017 Sep 11. Exp Hematol. 2018. PMID: 28911908 Free PMC article.

8

Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice.

Counsell JR, Karda R, Diaz JA, Carey L, Wiktorowicz T, Buckley SMK, Ameri S, Ng J, Baruteau J, Almeida F, de Silva R, Simone R, Lugarà E, Lignani G, Lindemann D, Rethwilm A, Rahim AA, Waddington SN, Howe SJ. Counsell JR, et al. Among authors: howe sj. Mol Ther Nucleic Acids. 2018 Sep 7;12:626-634. doi: 10.1016/j.omtn.2018.07.006. Epub 2018 Aug 3. Mol Ther Nucleic Acids. 2018. PMID: 30081233 Free PMC article.

9

Gene delivery of a mutant TGFβ3 reduces markers of scar tissue formation after cutaneous wounding.

Waddington SN, Crossley R, Sheard V, Howe SJ, Buckley SM, Coughlan L, Gilham DE, Hawkins RE, McKay TR. Waddington SN, et al. Among authors: howe sj. Mol Ther. 2010 Dec;18(12):2104-11. doi: 10.1038/mt.2010.174. Epub 2010 Aug 24. Mol Ther. 2010. PMID: 20736928 Free PMC article.

10

Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression.

Buckley SM, Howe SJ, Sheard V, Ward NJ, Coutelle C, Thrasher AJ, Waddington SN, McKay TR. Buckley SM, et al. Among authors: howe sj. Gene Ther. 2008 Aug;15(16):1167-75. doi: 10.1038/gt.2008.74. Epub 2008 Apr 24. Gene Ther. 2008. PMID: 18432275

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