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Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface.
Kroh HK, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi MD, Nyborg AC, Rainey GJ, Warrener P, Spiller BW, Lacy DB. Kroh HK, et al. Among authors: chandrasekaran r. J Biol Chem. 2017 Sep 1;292(35):14401-14412. doi: 10.1074/jbc.M117.781112. Epub 2017 Jul 13. J Biol Chem. 2017. PMID: 28705932 Free PMC article.
The role of toxins in Clostridium difficile infection.
Chandrasekaran R, Lacy DB. Chandrasekaran R, et al. FEMS Microbiol Rev. 2017 Nov 1;41(6):723-750. doi: 10.1093/femsre/fux048. FEMS Microbiol Rev. 2017. PMID: 29048477 Free PMC article. Review.
Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage.
Vijayan K, Visweswaran GRR, Chandrasekaran R, Trakhimets O, Brown SL, Watson A, Zuck M, Dambrauskas N, Raappana A, Carbonetti S, Kelnhofer-Millevolte L, Glennon EKK, Postiglione R, Sather DN, Kaushansky A. Vijayan K, et al. Among authors: chandrasekaran r. Cell Rep. 2021 Aug 3;36(5):109489. doi: 10.1016/j.celrep.2021.109489. Cell Rep. 2021. PMID: 34348141 Free article.
Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection.
Visweswaran GRR, Vijayan K, Chandrasekaran R, Trakhimets O, Brown SL, Vigdorovich V, Yang A, Raappana A, Watson A, Selman W, Zuck M, Dambrauskas N, Kaushansky A, Sather DN. Visweswaran GRR, et al. Among authors: chandrasekaran r. PLoS Pathog. 2022 Jul 6;18(7):e1010671. doi: 10.1371/journal.ppat.1010671. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35793394 Free PMC article.
249 results