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Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models.
Schultz L, Zurich MG, Culot M, da Costa A, Landry C, Bellwon P, Kristl T, Hörmann K, Ruzek S, Aiche S, Reinert K, Bielow C, Gosselet F, Cecchelli R, Huber CG, Schroeder OH, Gramowski-Voss A, Weiss DG, Bal-Price A. Schultz L, et al. Among authors: culot m. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):138-65. doi: 10.1016/j.tiv.2015.05.016. Epub 2015 May 27. Toxicol In Vitro. 2015. PMID: 26026931 Free article.
Peroxisome-proliferator-activated receptor-alpha activation protects brain capillary endothelial cells from oxygen-glucose deprivation-induced hyperpermeability in the blood-brain barrier.
Mysiorek C, Culot M, Dehouck L, Derudas B, Staels B, Bordet R, Cecchelli R, Fenart L, Berezowski V. Mysiorek C, et al. Among authors: culot m. Curr Neurovasc Res. 2009 Aug;6(3):181-93. doi: 10.2174/156720209788970081. Epub 2009 Aug 1. Curr Neurovasc Res. 2009. PMID: 19534718
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability.
De Bock M, Culot M, Wang N, Bol M, Decrock E, De Vuyst E, da Costa A, Dauwe I, Vinken M, Simon AM, Rogiers V, De Ley G, Evans WH, Bultynck G, Dupont G, Cecchelli R, Leybaert L. De Bock M, et al. Among authors: culot m. J Cereb Blood Flow Metab. 2011 Sep;31(9):1942-57. doi: 10.1038/jcbfm.2011.86. Epub 2011 Jun 8. J Cereb Blood Flow Metab. 2011. PMID: 21654699 Free PMC article.
59 results