Lozano G - Search Results

1

Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment.

Alexandrova EM, Yallowitz AR, Li D, Xu S, Schulz R, Proia DA, Lozano G, Dobbelstein M, Moll UM. Alexandrova EM, et al. Among authors: lozano g. Nature. 2015 Jul 16;523(7560):352-6. doi: 10.1038/nature14430. Epub 2015 May 25. Nature. 2015. PMID: 26009011 Free PMC article.

2

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53.

Montes de Oca Luna R, Wagner DS, Lozano G. Montes de Oca Luna R, et al. Among authors: lozano g. Nature. 1995 Nov 9;378(6553):203-6. doi: 10.1038/378203a0. Nature. 1995. PMID: 7477326

3

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.

Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G. Parant J, et al. Among authors: lozano g. Nat Genet. 2001 Sep;29(1):92-5. doi: 10.1038/ng714. Nat Genet. 2001. PMID: 11528400

4

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice.

Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, El-Naggar AK, Multani A, Chang S, Lozano G. Liu G, et al. Among authors: lozano g. Nat Genet. 2004 Jan;36(1):63-8. doi: 10.1038/ng1282. Epub 2003 Dec 21. Nat Genet. 2004. PMID: 14702042 Free article.

5

Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.

Xiong S, Van Pelt CS, Elizondo-Fraire AC, Fernandez-Garcia B, Lozano G. Xiong S, et al. Among authors: lozano g. Circulation. 2007 Jun 12;115(23):2925-30. doi: 10.1161/CIRCULATIONAHA.107.689901. Epub 2007 May 28. Circulation. 2007. PMID: 17533180

6

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss.

Terzian T, Suh YA, Iwakuma T, Post SM, Neumann M, Lang GA, Van Pelt CS, Lozano G. Terzian T, et al. Among authors: lozano g. Genes Dev. 2008 May 15;22(10):1337-44. doi: 10.1101/gad.1662908. Genes Dev. 2008. PMID: 18483220 Free PMC article.

7

20 years studying p53 functions in genetically engineered mice.

Donehower LA, Lozano G. Donehower LA, et al. Among authors: lozano g. Nat Rev Cancer. 2009 Nov;9(11):831-41. doi: 10.1038/nrc2731. Epub 2009 Sep 24. Nat Rev Cancer. 2009. PMID: 19776746 Review.

8

Mouse models of p53 functions.

Lozano G. Lozano G. Cold Spring Harb Perspect Biol. 2010 Apr;2(4):a001115. doi: 10.1101/cshperspect.a001115. Epub 2009 Dec 9. Cold Spring Harb Perspect Biol. 2010. PMID: 20452944 Free PMC article. Review.

9

You can win by losing: p53 mutations in rhabdomyosarcomas.

Post SM, Lozano G. Post SM, et al. Among authors: lozano g. J Pathol. 2010 Oct;222(2):124-8. doi: 10.1002/path.2757. J Pathol. 2010. PMID: 20821751

10

Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo.

Jackson JG, Post SM, Lozano G. Jackson JG, et al. Among authors: lozano g. J Pathol. 2011 Jan;223(2):127-36. doi: 10.1002/path.2783. Epub 2010 Oct 18. J Pathol. 2011. PMID: 20957626 Review.

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