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Page 1
Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis.
Ruggeri B, Nymberg C, Vuoksimaa E, Lourdusamy A, Wong CP, Carvalho FM, Jia T, Cattrell A, Macare C, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod PJ, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Nees F, Pausova Z, Paus T, Rietschel M, Robbins T, Smolka MN, Spanagel R, Bakalkin G, Mill J, Sommer WH, Rose RJ, Yan J, Aliev F, Dick D, Kaprio J, Desrivières S, Schumann G; IMAGEN Consortium. Ruggeri B, et al. Among authors: bakalkin g. Am J Psychiatry. 2015 Jun;172(6):543-52. doi: 10.1176/appi.ajp.2014.14030382. Epub 2015 May 18. Am J Psychiatry. 2015. PMID: 25982659 Free PMC article.
Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking.
Dong L, Bilbao A, Laucht M, Henriksson R, Yakovleva T, Ridinger M, Desrivieres S, Clarke TK, Lourdusamy A, Smolka MN, Cichon S, Blomeyer D, Treutlein J, Perreau-Lenz S, Witt S, Leonardi-Essmann F, Wodarz N, Zill P, Soyka M, Albrecht U, Rietschel M, Lathrop M, Bakalkin G, Spanagel R, Schumann G. Dong L, et al. Among authors: bakalkin g. Am J Psychiatry. 2011 Oct;168(10):1090-8. doi: 10.1176/appi.ajp.2011.10111579. Epub 2011 Aug 9. Am J Psychiatry. 2011. PMID: 21828288 Free article.
Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents.
Ruggeri B, Macare C, Stopponi S, Jia T, Carvalho FM, Robert G, Banaschewski T, Bokde ALW, Bromberg U, Büchel C, Cattrell A, Conrod PJ, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Nees F, Papadopoulos-Orfanos D, Paus T, Poustka L, Smolka MN, Vetter NC, Walter H, Whelan R, Sommer WH, Bakalkin G, Ciccocioppo R, Schumann G; IMAGEN consortium. Ruggeri B, et al. Among authors: bakalkin g. J Child Psychol Psychiatry. 2018 Jun;59(6):650-658. doi: 10.1111/jcpp.12843. Epub 2017 Dec 2. J Child Psychol Psychiatry. 2018. PMID: 29197086 Free PMC article.
Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse.
Tay N, Macare C, Liu Y, Ruggeri B, Jia T, Chu C, Biondo F, Ing A, Luo Q, Sarkysian D, Banaschewski T, Barker GJ, Bokde ALW, Bromberg U, Büchel C, Quinlan EB, Desrivières S, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Artiges E, Nees F, Orfanos DP, Paus T, Poustka L, Hohmann S, Fröhner JH, Smolka MN, Walter H, Whelan R, Frieling H, Bleich S, Barker ED, Syvänen AC, Rüegg J, Ekström TJ, Bakalkin G, Schumann G; IMAGEN Consortium. Tay N, et al. Among authors: bakalkin g. Am J Psychiatry. 2019 Feb 1;176(2):146-155. doi: 10.1176/appi.ajp.2018.17121360. Epub 2018 Dec 11. Am J Psychiatry. 2019. PMID: 30525907
Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence.
Meng W, Sjöholm LK, Kononenko O, Tay N, Zhang D, Sarkisyan D, Geske JR, Ing A, Qiu W, Watanabe H, Almamoun R, Frieling H, Bleich S, Cui D, Biernacka JM, Mayfield RD, Dang Y, Karpyak VM, Schumann G; IMAGEN Consortium; Bakalkin G, Ekström TJ, Rüegg J, Liu Y. Meng W, et al. Among authors: bakalkin g. Mol Psychiatry. 2021 Aug;26(8):4367-4382. doi: 10.1038/s41380-019-0588-9. Epub 2019 Nov 19. Mol Psychiatry. 2021. PMID: 31745236
Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group.
Jia T, Chu C, Liu Y, van Dongen J, Papastergios E, Armstrong NJ, Bastin ME, Carrillo-Roa T, den Braber A, Harris M, Jansen R, Liu J, Luciano M, Ori APS, Roiz Santiañez R, Ruggeri B, Sarkisyan D, Shin J, Sungeun K, Tordesillas Gutiérrez D, Van't Ent D, Ames D, Artiges E, Bakalkin G, Banaschewski T, Bokde ALW, Brodaty H, Bromberg U, Brouwer R, Büchel C, Burke Quinlan E, Cahn W, de Zubicaray GI, Ehrlich S, Ekström TJ, Flor H, Fröhner JH, Frouin V, Garavan H, Gowland P, Heinz A, Hoare J, Ittermann B, Jahanshad N, Jiang J, Kwok JB, Martin NG, Martinot JL, Mather KA, McMahon KL, McRae AF, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Sämann PG, Schofield PR, Smolka MN, Stein DJ, Strike LT, Teeuw J, Thalamuthu A, Trollor J, Walter H, Wardlaw JM, Wen W, Whelan R, Apostolova LG, Binder EB, Boomsma DI, Calhoun V, Crespo-Facorro B, Deary IJ, Hulshoff Pol H, Ophoff RA, Pausova Z, Sachdev PS, Saykin A, Wright MJ, Thompson PM, Schumann G, Desrivières S. Jia T, et al. Among authors: bakalkin g. Mol Psychiatry. 2021 Aug;26(8):3884-3895. doi: 10.1038/s41380-019-0605-z. Epub 2019 Dec 6. Mol Psychiatry. 2021. PMID: 31811260 Free PMC article.
The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study.
Müller CP, Chu C, Qin L, Liu C, Xu B, Gao H, Ruggeri B, Hieber S, Schneider J, Jia T, Tay N, Akira S, Satoh T, Banaschewski T, Bokde ALW, Bromberg U, Büchel C, Quinlan EB, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Artiges E, Lemaitre H, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Bakalkin G, Liu Y, Desrivières S, Elliott P, Eulenburg V, Levy D, Crews F, Schumann G. Müller CP, et al. Among authors: bakalkin g. Cereb Cortex. 2019 Apr 1;29(4):1736-1751. doi: 10.1093/cercor/bhy341. Cereb Cortex. 2019. PMID: 30721969 Free PMC article.
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proença C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esko T, Fernández-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Núñez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tönjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, D… See abstract for full author list ➔ Schumann G, et al. Among authors: bakalkin g. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7119-24. doi: 10.1073/pnas.1017288108. Epub 2011 Apr 6. Proc Natl Acad Sci U S A. 2011. PMID: 21471458 Free PMC article.
Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum.
Zillich L, Poisel E, Frank J, Foo JC, Friske MM, Streit F, Sirignano L, Heilmann-Heimbach S, Heimbach A, Hoffmann P, Degenhardt F, Hansson AC, Bakalkin G, Nöthen MM, Rietschel M, Spanagel R, Witt SH. Zillich L, et al. Among authors: bakalkin g. Transl Psychiatry. 2022 May 6;12(1):190. doi: 10.1038/s41398-022-01959-1. Transl Psychiatry. 2022. PMID: 35523767 Free PMC article.
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.
Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, Ruggeri B, Amin N, Jia T, Preis S, Segura Lepe M, Akira S, Barbieri C, Baumeister S, Cauchi S, Clarke TK, Enroth S, Fischer K, Hällfors J, Harris SE, Hieber S, Hofer E, Hottenga JJ, Johansson Å, Joshi PK, Kaartinen N, Laitinen J, Lemaitre R, Loukola A, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Mbarek H, Milaneschi Y, Moayyeri A, Mukamal K, Nelson C, Nettleton J, Partinen E, Rawal R, Robino A, Rose L, Sala C, Satoh T, Schmidt R, Schraut K, Scott R, Smith AV, Starr JM, Teumer A, Trompet S, Uitterlinden AG, Venturini C, Vergnaud AC, Verweij N, Vitart V, Vuckovic D, Wedenoja J, Yengo L, Yu B, Zhang W, Zhao JH, Boomsma DI, Chambers J, Chasman DI, Daniela T, de Geus E, Deary I, Eriksson JG, Esko T, Eulenburg V, Franco OH, Froguel P, Gieger C, Grabe HJ, Gudnason V, Gyllensten U, Harris TB, Hartikainen AL, Heath AC, Hocking L, Hofman A, Huth C, Jarvelin MR, Jukema JW, Kaprio J, Kooner JS, Kutalik Z, Lahti J, Langenberg C, Lehtimäki T, Liu Y, Madden PA, Martin N, Morrison A, Penninx B, Pirastu N, Psaty B, Raitakari O, Ridker P, Rose R, Rotter JI, Samani NJ, Schmidt H, Spector TD, Stott D, Strachan D, Tzoulaki I, van der Harst P, v… See abstract for full author list ➔ Schumann G, et al. Among authors: bakalkin g. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14372-14377. doi: 10.1073/pnas.1611243113. Epub 2016 Nov 28. Proc Natl Acad Sci U S A. 2016. PMID: 27911795 Free PMC article.
153 results