de Sauvage FJ - Search Results

1

Translational value of mouse models in oncology drug development.

Gould SE, Junttila MR, de Sauvage FJ. Gould SE, et al. Among authors: de sauvage fj. Nat Med. 2015 May;21(5):431-9. doi: 10.1038/nm.3853. Nat Med. 2015. PMID: 25951530

2

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice.

Erickson SL, de Sauvage FJ, Kikly K, Carver-Moore K, Pitts-Meek S, Gillett N, Sheehan KC, Schreiber RD, Goeddel DV, Moore MW. Erickson SL, et al. Among authors: de sauvage fj. Nature. 1994 Dec 8;372(6506):560-3. doi: 10.1038/372560a0. Nature. 1994. PMID: 7990930

3

Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection.

Peters BA, Kan Z, Sebisanovic D, Pujara K, Wang Z, Hong P, Chow B, Stinson J, Carlton VE, Pham TQ, Stern H, Waring P, Hillan KJ, Eberhard DA, de Sauvage F, Zheng J, Faham M, Seshagiri S. Peters BA, et al. Nat Methods. 2007 Sep;4(9):713-5. doi: 10.1038/nmeth1081. Epub 2007 Aug 19. Nat Methods. 2007. PMID: 17704782

4

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens.

Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, Gong Q, Abbas AR, Modrusan Z, Ghilardi N, de Sauvage FJ, Ouyang W. Zheng Y, et al. Among authors: de sauvage fj. Nat Med. 2008 Mar;14(3):282-9. doi: 10.1038/nm1720. Epub 2008 Feb 10. Nat Med. 2008. PMID: 18264109

5

A paracrine requirement for hedgehog signalling in cancer.

Yauch RL, Gould SE, Scales SJ, Tang T, Tian H, Ahn CP, Marshall D, Fu L, Januario T, Kallop D, Nannini-Pepe M, Kotkow K, Marsters JC, Rubin LL, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Nature. 2008 Sep 18;455(7211):406-10. doi: 10.1038/nature07275. Epub 2008 Aug 27. Nature. 2008. PMID: 18754008

6

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.

Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, Gilliland DG. Hofmann I, et al. Among authors: de sauvage fj. Cell Stem Cell. 2009 Jun 5;4(6):559-67. doi: 10.1016/j.stem.2009.03.016. Cell Stem Cell. 2009. PMID: 19497284 Free PMC article.

7

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449.

Rudin CM, Hann CL, Laterra J, Yauch RL, Callahan CA, Fu L, Holcomb T, Stinson J, Gould SE, Coleman B, LoRusso PM, Von Hoff DD, de Sauvage FJ, Low JA. Rudin CM, et al. Among authors: de sauvage fj. N Engl J Med. 2009 Sep 17;361(12):1173-8. doi: 10.1056/NEJMoa0902903. Epub 2009 Sep 2. N Engl J Med. 2009. PMID: 19726761 Free PMC article.

8

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

Yauch RL, Dijkgraaf GJ, Alicke B, Januario T, Ahn CP, Holcomb T, Pujara K, Stinson J, Callahan CA, Tang T, Bazan JF, Kan Z, Seshagiri S, Hann CL, Gould SE, Low JA, Rudin CM, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Science. 2009 Oct 23;326(5952):572-4. doi: 10.1126/science.1179386. Epub 2009 Sep 2. Science. 2009. PMID: 19726788 Free PMC article.

9

The mutation spectrum revealed by paired genome sequences from a lung cancer patient.

Lee W, Jiang Z, Liu J, Haverty PM, Guan Y, Stinson J, Yue P, Zhang Y, Pant KP, Bhatt D, Ha C, Johnson S, Kennemer MI, Mohan S, Nazarenko I, Watanabe C, Sparks AB, Shames DS, Gentleman R, de Sauvage FJ, Stern H, Pandita A, Ballinger DG, Drmanac R, Modrusan Z, Seshagiri S, Zhang Z. Lee W, et al. Among authors: de sauvage fj. Nature. 2010 May 27;465(7297):473-7. doi: 10.1038/nature09004. Nature. 2010. PMID: 20505728

10

Second generation 2-pyridyl biphenyl amide inhibitors of the hedgehog pathway.

Castanedo GM, Wang S, Robarge KD, Blackwood E, Burdick D, Chang C, Dijkgraaf GJ, Gould S, Gunzner J, Guichert O, Halladay J, Khojasteh C, Lee L, Marsters JC Jr, Murray L, Peterson D, Plise E, Salphati L, de Sauvage FJ, Wong S, Sutherlin DP. Castanedo GM, et al. Among authors: de sauvage fj. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6748-53. doi: 10.1016/j.bmcl.2010.08.134. Epub 2010 Sep 15. Bioorg Med Chem Lett. 2010. PMID: 20875741

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

184 results

Search Page