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Selective elimination of mitochondrial mutations in the germline by genome editing.
Reddy P, Ocampo A, Suzuki K, Luo J, Bacman SR, Williams SL, Sugawara A, Okamura D, Tsunekawa Y, Wu J, Lam D, Xiong X, Montserrat N, Esteban CR, Liu GH, Sancho-Martinez I, Manau D, Civico S, Cardellach F, Del Mar O'Callaghan M, Campistol J, Zhao H, Campistol JM, Moraes CT, Izpisua Belmonte JC. Reddy P, et al. Among authors: xiong x. Cell. 2015 Apr 23;161(3):459-469. doi: 10.1016/j.cell.2015.03.051. Cell. 2015. PMID: 25910206 Free PMC article.
Synthetic biology for therapeutic applications.
Abil Z, Xiong X, Zhao H. Abil Z, et al. Among authors: xiong x. Mol Pharm. 2015 Feb 2;12(2):322-31. doi: 10.1021/mp500392q. Epub 2014 Aug 13. Mol Pharm. 2015. PMID: 25098838 Free PMC article. Review.
TALEN outperforms Cas9 in editing heterochromatin target sites.
Jain S, Shukla S, Yang C, Zhang M, Fatma Z, Lingamaneni M, Abesteh S, Lane ST, Xiong X, Wang Y, Schroeder CM, Selvin PR, Zhao H. Jain S, et al. Among authors: xiong x. Nat Commun. 2021 Jan 27;12(1):606. doi: 10.1038/s41467-020-20672-5. Nat Commun. 2021. PMID: 33504770 Free PMC article.
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation.
Kubo N, Ishii H, Xiong X, Bianco S, Meitinger F, Hu R, Hocker JD, Conte M, Gorkin D, Yu M, Li B, Dixon JR, Hu M, Nicodemi M, Zhao H, Ren B. Kubo N, et al. Among authors: xiong x. Nat Struct Mol Biol. 2021 Feb;28(2):152-161. doi: 10.1038/s41594-020-00539-5. Epub 2021 Jan 4. Nat Struct Mol Biol. 2021. PMID: 33398174 Free PMC article.
5,673 results