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A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.
Mothe B, Hu X, Llano A, Rosati M, Olvera A, Kulkarni V, Valentin A, Alicea C, Pilkington GR, Sardesai NY, Rocafort M, Crespo M, Carrillo J, Marco A, Mullins JI, Dorrell L, Hanke T, Clotet B, Pavlakis GN, Felber BK, Brander C. Mothe B, et al. Among authors: alicea c. J Transl Med. 2015 Feb 15;13:60. doi: 10.1186/s12967-015-0392-5. J Transl Med. 2015. PMID: 25879820 Free PMC article.
Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques.
Kulkarni V, Jalah R, Ganneru B, Bergamaschi C, Alicea C, von Gegerfelt A, Patel V, Zhang GM, Chowdhury B, Broderick KE, Sardesai NY, Valentin A, Rosati M, Felber BK, Pavlakis GN. Kulkarni V, et al. Among authors: alicea c. Vaccine. 2011 Sep 9;29(39):6742-54. doi: 10.1016/j.vaccine.2010.12.056. Epub 2010 Dec 30. Vaccine. 2011. PMID: 21195080 Free PMC article.
IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques.
Jalah R, Patel V, Kulkarni V, Rosati M, Alicea C, Ganneru B, von Gegerfelt A, Huang W, Guan Y, Broderick KE, Sardesai NY, LaBranche C, Montefiori DC, Pavlakis GN, Felber BK. Jalah R, et al. Among authors: alicea c. Hum Vaccin Immunother. 2012 Nov 1;8(11):1620-9. doi: 10.4161/hv.21407. Epub 2012 Aug 16. Hum Vaccin Immunother. 2012. PMID: 22894956 Free PMC article.
HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice.
Kulkarni V, Rosati M, Valentin A, Ganneru B, Singh AK, Yan J, Rolland M, Alicea C, Beach RK, Zhang GM, Le Gall S, Broderick KE, Sardesai NY, Heckerman D, Mothe B, Brander C, Weiner DB, Mullins JI, Pavlakis GN, Felber BK. Kulkarni V, et al. Among authors: alicea c. PLoS One. 2013;8(3):e60245. doi: 10.1371/journal.pone.0060245. Epub 2013 Mar 28. PLoS One. 2013. PMID: 23555935 Free PMC article.
Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques.
Kulkarni V, Valentin A, Rosati M, Alicea C, Singh AK, Jalah R, Broderick KE, Sardesai NY, Le Gall S, Mothe B, Brander C, Rolland M, Mullins JI, Pavlakis GN, Felber BK. Kulkarni V, et al. Among authors: alicea c. PLoS One. 2014 Jan 23;9(1):e86254. doi: 10.1371/journal.pone.0086254. eCollection 2014. PLoS One. 2014. PMID: 24465991 Free PMC article.
Comparative analysis of SIV-specific cellular immune responses induced by different vaccine platforms in rhesus macaques.
Valentin A, McKinnon K, Li J, Rosati M, Kulkarni V, Pilkington GR, Bear J, Alicea C, Vargas-Inchaustegui DA, Jean Patterson L, Pegu P, Liyanage NPM, Gordon SN, Vaccari M, Wang Y, Hogg AE, Frey B, Sui Y, Reed SG, Sardesai NY, Berzofsky JA, Franchini G, Robert-Guroff M, Felber BK, Pavlakis GN. Valentin A, et al. Among authors: alicea c. Clin Immunol. 2014 Nov;155(1):91-107. doi: 10.1016/j.clim.2014.09.005. Epub 2014 Sep 16. Clin Immunol. 2014. PMID: 25229164 Free PMC article.
DNA is an efficient booster of dendritic cell-based vaccine.
Li J, Valentin A, Beach RK, Alicea C, Felber BK, Pavlakis GN. Li J, et al. Among authors: alicea c. Hum Vaccin Immunother. 2015;11(8):1927-35. doi: 10.1080/21645515.2015.1020265. Hum Vaccin Immunother. 2015. PMID: 26125100 Free PMC article.
47 results