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BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.
Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen PI, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ, Rabinovitch M. Diebold I, et al. Among authors: hopper rk. Cell Metab. 2015 Apr 7;21(4):596-608. doi: 10.1016/j.cmet.2015.03.010. Cell Metab. 2015. PMID: 25863249 Free PMC article.
FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.
Spiekerkoetter E, Tian X, Cai J, Hopper RK, Sudheendra D, Li CG, El-Bizri N, Sawada H, Haghighat R, Chan R, Haghighat L, de Jesus Perez V, Wang L, Reddy S, Zhao M, Bernstein D, Solow-Cordero DE, Beachy PA, Wandless TJ, Ten Dijke P, Rabinovitch M. Spiekerkoetter E, et al. Among authors: hopper rk. J Clin Invest. 2013 Aug;123(8):3600-13. doi: 10.1172/JCI65592. Epub 2013 Jul 15. J Clin Invest. 2013. PMID: 23867624 Free PMC article.
RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.
Rhodes CJ, Im H, Cao A, Hennigs JK, Wang L, Sa S, Chen PI, Nickel NP, Miyagawa K, Hopper RK, Tojais NF, Li CG, Gu M, Spiekerkoetter E, Xian Z, Chen R, Zhao M, Kaschwich M, Del Rosario PA, Bernstein D, Zamanian RT, Wu JC, Snyder MP, Rabinovitch M. Rhodes CJ, et al. Among authors: hopper rk. Am J Respir Crit Care Med. 2015 Aug 1;192(3):356-66. doi: 10.1164/rccm.201408-1528OC. Am J Respir Crit Care Med. 2015. PMID: 26030479 Free PMC article.
Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-β in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension.
Tojais NF, Cao A, Lai YJ, Wang L, Chen PI, Alcazar MAA, de Jesus Perez VA, Hopper RK, Rhodes CJ, Bill MA, Sakai LY, Rabinovitch M. Tojais NF, et al. Among authors: hopper rk. Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1559-1569. doi: 10.1161/ATVBAHA.117.309696. Epub 2017 Jun 15. Arterioscler Thromb Vasc Biol. 2017. PMID: 28619995 Free PMC article.
Settling the Score in Pulmonary Hypertension?
Hopper RK, Cornfield DN. Hopper RK, et al. Pediatr Crit Care Med. 2018 Aug;19(8):782-783. doi: 10.1097/PCC.0000000000001651. Pediatr Crit Care Med. 2018. PMID: 30095716 No abstract available.
Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry.
Ong MS, Abman S, Austin ED, Feinstein JA, Hopper RK, Krishnan US, Mullen MP, Natter MD, Raj JU, Rosenzweig EB, Mandl KD; Pediatric Pulmonary Hypertension Network and National Heart, Lung, and Blood Institute Pediatric Pulmonary Vascular Disease Outcomes Bioinformatics Clinical Coordinating Center Investigators. Ong MS, et al. Among authors: hopper rk. J Pediatr. 2019 Aug;211:63-71.e6. doi: 10.1016/j.jpeds.2019.04.046. Epub 2019 Jun 5. J Pediatr. 2019. PMID: 31176455 Free PMC article.
Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances.
Maron BA, Abman SH, Elliott CG, Frantz RP, Hopper RK, Horn EM, Nicolls MR, Shlobin OA, Shah SJ, Kovacs G, Olschewski H, Rosenzweig EB. Maron BA, et al. Among authors: hopper rk. Am J Respir Crit Care Med. 2021 Jun 15;203(12):1472-1487. doi: 10.1164/rccm.202012-4317SO. Am J Respir Crit Care Med. 2021. PMID: 33861689 Free PMC article.
51 results