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Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure.
Lakshmikanthan S, Zieba BJ, Ge ZD, Momotani K, Zheng X, Lund H, Artamonov MV, Maas JE, Szabo A, Zhang DX, Auchampach JA, Mattson DL, Somlyo AV, Chrzanowska-Wodnicka M. Lakshmikanthan S, et al. Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1486-94. doi: 10.1161/ATVBAHA.114.303678. Epub 2014 May 1. Arterioscler Thromb Vasc Biol. 2014. PMID: 24790136 Free PMC article.
Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling.
Balaji Ragunathrao VA, Anwar M, Akhter MZ, Chavez A, Mao Y, Natarajan V, Lakshmikanthan S, Chrzanowska-Wodnicka M, Dudek AZ, Claesson-Welsh L, Kitajewski JK, Wary KK, Malik AB, Mehta D. Balaji Ragunathrao VA, et al. Among authors: lakshmikanthan s. Cell Rep. 2019 Dec 10;29(11):3472-3487.e4. doi: 10.1016/j.celrep.2019.11.036. Cell Rep. 2019. PMID: 31825830 Free PMC article.
Endothelial Rap1 (Ras-Association Proximate 1) Restricts Inflammatory Signaling to Protect From the Progression of Atherosclerosis.
Singh B, Kosuru R, Lakshmikanthan S, Sorci-Thomas MG, Zhang DX, Sparapani R, Vasquez-Vivar J, Chrzanowska M. Singh B, et al. Among authors: lakshmikanthan s. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):638-650. doi: 10.1161/ATVBAHA.120.315401. Epub 2020 Dec 3. Arterioscler Thromb Vasc Biol. 2021. PMID: 33267664 Free PMC article.
Distinct Signaling Functions of Rap1 Isoforms in NO Release From Endothelium.
Kosuru R, Singh B, Lakshmikanthan S, Nishijima Y, Vasquez-Vivar J, Zhang DX, Chrzanowska M. Kosuru R, et al. Among authors: lakshmikanthan s. Front Cell Dev Biol. 2021 Jun 17;9:687598. doi: 10.3389/fcell.2021.687598. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34222255 Free PMC article.
15 results