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Durable complete responses off all treatment in patients with metastatic malignant melanoma after sequential immunotherapy followed by a finite course of BRAF inhibitor therapy.
Wyluda EJ, Cheng J, Schell TD, Haley JS, Mallon C, Neves RI, Robertson G, Sivik J, Mackley H, Talamo G, Drabick JJ. Wyluda EJ, et al. Among authors: sivik j. Cancer Biol Ther. 2015;16(5):662-70. doi: 10.1080/15384047.2015.1026507. Cancer Biol Ther. 2015. PMID: 25806780 Free PMC article.
Preliminary observations indicate variable patterns of plasma 5-fluorouracil (5-FU) levels during dose optimization of infusional 5-FU in colorectal cancer patients.
Kline CL, Sheikh HS, Scicchitano A, Gingrich R, Beachler C, Finnberg NK, Liao J, Sivik J, El-Deiry WS. Kline CL, et al. Among authors: sivik j. Cancer Biol Ther. 2011 Oct 1;12(7):557-68. doi: 10.4161/cbt.12.7.18059. Epub 2011 Oct 1. Cancer Biol Ther. 2011. PMID: 21931273 Free article. Clinical Trial.
Personalized dosing via pharmacokinetic monitoring of 5-fluorouracil might reduce toxicity in early- or late-stage colorectal cancer patients treated with infusional 5-fluorouracil-based chemotherapy regimens.
Kline CL, Schiccitano A, Zhu J, Beachler C, Sheikh H, Harvey HA, Mackley HB, McKenna K, Staveley-O'Carroll K, Poritz L, Messaris E, Stewart D, Sivik J, El-Deiry WS. Kline CL, et al. Among authors: sivik j. Clin Colorectal Cancer. 2014 Jun;13(2):119-26. doi: 10.1016/j.clcc.2013.11.001. Epub 2013 Nov 20. Clin Colorectal Cancer. 2014. PMID: 24461492
Eomes+T-betlow CD8+ T Cells Are Functionally Impaired and Are Associated with Poor Clinical Outcome in Patients with Acute Myeloid Leukemia.
Jia B, Zhao C, Rakszawski KL, Claxton DF, Ehmann WC, Rybka WB, Mineishi S, Wang M, Shike H, Bayerl MG, Sivik JM, Schell TD, Drabick JJ, Hohl RJ, Zheng H. Jia B, et al. Among authors: sivik jm. Cancer Res. 2019 Apr 1;79(7):1635-1645. doi: 10.1158/0008-5472.CAN-18-3107. Epub 2019 Feb 1. Cancer Res. 2019. PMID: 30709927
31 results