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Page 1
A novel Alzheimer disease locus located near the gene encoding tau protein.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH Jr, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L; IGAP Consortium; Haines JL, Psaty B… See abstract for full author list ➔ Jun G, et al. Among authors: cruchaga c. Mol Psychiatry. 2016 Jan;21(1):108-17. doi: 10.1038/mp.2015.23. Epub 2015 Mar 17. Mol Psychiatry. 2016. PMID: 25778476 Free PMC article.
Complexities of cerebral small vessel disease, blood pressure, and dementia relationship: new insights from genetics.
Sargurupremraj M, Soumare A, Bis JC, Surakka I, Jurgenson T, Joly P, Knol MJ, Wang R, Yang Q, Satizabal CL, Gudjonsson A, Mishra A, Bouteloup V, Phuah CL, van Duijn CM, Cruchaga C, Dufouil C, Chêne G, Lopez O, Psaty BM, Tzourio C, Amouyel P, Adams HH, Jacqmin-Gadda H, Ikram MA, Gudnason V, Milani L, Winsvold BS, Hveem K, Matthews PM, Longstreth WT, Seshadri S, Launer LJ, Debette S. Sargurupremraj M, et al. Among authors: cruchaga c. medRxiv [Preprint]. 2023 Aug 13:2023.08.08.23293761. doi: 10.1101/2023.08.08.23293761. medRxiv. 2023. Update in: JAMA Netw Open. 2024 May 1;7(5):e2412824. doi: 10.1001/jamanetworkopen.2024.12824. PMID: 37790435 Free PMC article. Updated. Preprint.
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.
Drieu A, Du S, Storck SE, Rustenhoven J, Papadopoulos Z, Dykstra T, Zhong F, Kim K, Blackburn S, Mamuladze T, Harari O, Karch CM, Bateman RJ, Perrin R, Farlow M, Chhatwal J; Dominantly Inherited Alzheimer Network; Hu S, Randolph GJ, Smirnov I, Kipnis J. Drieu A, et al. Nature. 2022 Nov;611(7936):585-593. doi: 10.1038/s41586-022-05397-3. Epub 2022 Nov 9. Nature. 2022. PMID: 36352225 Free PMC article.
Harmonization of CSF and imaging biomarkers for Alzheimer's disease biomarkers: need and practical applications for genetics studies and preclinical classification.
Timsina J, Ali M, Do A, Wang L, Sung YJ, Cruchaga C. Timsina J, et al. Among authors: cruchaga c. bioRxiv [Preprint]. 2023 May 24:2023.05.24.542118. doi: 10.1101/2023.05.24.542118. bioRxiv. 2023. Update in: Neurobiol Dis. 2024 Jan;190:106373. doi: 10.1016/j.nbd.2023.106373. PMID: 37292823 Free PMC article. Updated. Preprint.
Epistatic Features and Machine Learning Improve Alzheimer's Risk Prediction Over Polygenic Risk Scores.
Hermes S, Cady J, Armentrout S, O'Connor J, Carlson S, Cruchaga C, Wingo T, Greytak EM; Alzheimer’s Disease Neuroimaging Initiative. Hermes S, et al. Among authors: cruchaga c. medRxiv [Preprint]. 2023 Mar 15:2023.02.10.23285766. doi: 10.1101/2023.02.10.23285766. medRxiv. 2023. Update in: J Alzheimers Dis. 2024;99(4):1425-1440. doi: 10.3233/JAD-230236. PMID: 36798198 Free PMC article. Updated. Preprint.
Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease.
Girard TJ, Antunes L, Zhang N, Amrute JM, Subramanian R, Eldem I, Remy KE, Mazer M, Erlich EC, Cruchaga C, Steed AL, Randolph GJ, Di Paola J. Girard TJ, et al. Among authors: cruchaga c. J Thromb Haemost. 2023 Mar;21(3):629-638. doi: 10.1016/j.jtha.2022.11.033. Epub 2022 Dec 22. J Thromb Haemost. 2023. PMID: 36696180 Free PMC article.
Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performance.
Anastasi F, Genius P, Rodriguez-Fernandez B, Yang C, Gorijala P, Timsina J, Hernández-Villamizar F, Lorenzini L, Del Campo M, Sanchez-Benavides G, Minguillon C, Navarro A, Cruchaga C, Suárez-Calvet M, Vilor-Tejedor N. Anastasi F, et al. Among authors: cruchaga c. Res Sq [Preprint]. 2024 Oct 18:rs.3.rs-5267673. doi: 10.21203/rs.3.rs-5267673/v1. Res Sq. 2024. PMID: 39483923 Free PMC article. Preprint.
434 results