Westphal D - Search Results

1

Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains.

Iyer S, Bell F, Westphal D, Anwari K, Gulbis J, Smith BJ, Dewson G, Kluck RM. Iyer S, et al. Among authors: westphal d. Cell Death Differ. 2015 Oct;22(10):1665-75. doi: 10.1038/cdd.2015.15. Epub 2015 Mar 6. Cell Death Differ. 2015. PMID: 25744027 Free PMC article.

2

Bak apoptotic function is not directly regulated by phosphorylation.

Tran VH, Bartolo R, Westphal D, Alsop A, Dewson G, Kluck RM. Tran VH, et al. Among authors: westphal d. Cell Death Dis. 2013 Jan 10;4(1):e452. doi: 10.1038/cddis.2012.191. Cell Death Dis. 2013. PMID: 23303126 Free PMC article.

3

Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis.

Westphal D, Kluck RM, Dewson G. Westphal D, et al. Cell Death Differ. 2014 Feb;21(2):196-205. doi: 10.1038/cdd.2013.139. Epub 2013 Oct 25. Cell Death Differ. 2014. PMID: 24162660 Free PMC article. Review.

4

Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.

Czabotar PE, Westphal D, Dewson G, Ma S, Hockings C, Fairlie WD, Lee EF, Yao S, Robin AY, Smith BJ, Huang DC, Kluck RM, Adams JM, Colman PM. Czabotar PE, et al. Among authors: westphal d. Cell. 2013 Jan 31;152(3):519-31. doi: 10.1016/j.cell.2012.12.031. Cell. 2013. PMID: 23374347 Free article.

5

Bak core and latch domains separate during activation, and freed core domains form symmetric homodimers.

Brouwer JM, Westphal D, Dewson G, Robin AY, Uren RT, Bartolo R, Thompson GV, Colman PM, Kluck RM, Czabotar PE. Brouwer JM, et al. Among authors: westphal d. Mol Cell. 2014 Sep 18;55(6):938-946. doi: 10.1016/j.molcel.2014.07.016. Epub 2014 Aug 28. Mol Cell. 2014. PMID: 25175025 Free article.

6

Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane.

Westphal D, Dewson G, Menard M, Frederick P, Iyer S, Bartolo R, Gibson L, Czabotar PE, Smith BJ, Adams JM, Kluck RM. Westphal D, et al. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4076-85. doi: 10.1073/pnas.1415142111. Epub 2014 Sep 16. Proc Natl Acad Sci U S A. 2014. PMID: 25228770 Free PMC article.

7

Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.

Robin AY, Krishna Kumar K, Westphal D, Wardak AZ, Thompson GV, Dewson G, Colman PM, Czabotar PE. Robin AY, et al. Among authors: westphal d. Cell Death Dis. 2015 Jul 9;6(7):e1809. doi: 10.1038/cddis.2015.141. Cell Death Dis. 2015. PMID: 26158515 Free PMC article.

8

Molecular biology of Bax and Bak activation and action.

Westphal D, Dewson G, Czabotar PE, Kluck RM. Westphal D, et al. Biochim Biophys Acta. 2011 Apr;1813(4):521-31. doi: 10.1016/j.bbamcr.2010.12.019. Epub 2010 Dec 30. Biochim Biophys Acta. 2011. PMID: 21195116 Free article. Review.

9

BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association.

Dengler MA, Robin AY, Gibson L, Li MX, Sandow JJ, Iyer S, Webb AI, Westphal D, Dewson G, Adams JM. Dengler MA, et al. Among authors: westphal d. Cell Rep. 2019 Apr 9;27(2):359-373.e6. doi: 10.1016/j.celrep.2019.03.040. Cell Rep. 2019. PMID: 30970242 Free article.

10

NMR studies of interactions between Bax and BH3 domain-containing peptides in the absence and presence of CHAPS.

Yao S, Westphal D, Babon JJ, Thompson GV, Robin AY, Adams JM, Colman PM, Czabotar PE. Yao S, et al. Among authors: westphal d. Arch Biochem Biophys. 2014 Mar 1;545:33-43. doi: 10.1016/j.abb.2014.01.003. Epub 2014 Jan 13. Arch Biochem Biophys. 2014. PMID: 24434006

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

163 results

Search Page

Filters