Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J.
Marcheva B, et al. Among authors: ramsey km.
Nature. 2010 Jul 29;466(7306):627-31. doi: 10.1038/nature09253.
Nature. 2010.
PMID: 20562852
Free PMC article.