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Structural divergence of the rotary ATPases.
Muench SP, Trinick J, Harrison MA. Muench SP, et al. Q Rev Biophys. 2011 Aug;44(3):311-56. doi: 10.1017/S0033583510000338. Epub 2011 Mar 22. Q Rev Biophys. 2011. PMID: 21426606 Review.
Flexibility within the rotor and stators of the vacuolar H+-ATPase.
Song CF, Papachristos K, Rawson S, Huss M, Wieczorek H, Paci E, Trinick J, Harrison MA, Muench SP. Song CF, et al. Among authors: muench sp. PLoS One. 2013 Dec 2;8(12):e82207. doi: 10.1371/journal.pone.0082207. eCollection 2013. PLoS One. 2013. PMID: 24312643 Free PMC article.
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target.
Wilkinson C, McPhillie MJ, Zhou Y, Woods S, Afanador GA, Rawson S, Khaliq F, Prigge ST, Roberts CW, Rice DW, McLeod R, Fishwick CW, Muench SP. Wilkinson C, et al. Among authors: muench sp. Bioorg Med Chem Lett. 2014 Feb 1;24(3):911-6. doi: 10.1016/j.bmcl.2013.12.066. Epub 2013 Dec 22. Bioorg Med Chem Lett. 2014. PMID: 24398298 Free PMC article.
130 results