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mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.
Damsky W, Micevic G, Meeth K, Muthusamy V, Curley DP, Santhanakrishnan M, Erdelyi I, Platt JT, Huang L, Theodosakis N, Zaidi MR, Tighe S, Davies MA, Dankort D, McMahon M, Merlino G, Bardeesy N, Bosenberg M. Damsky W, et al. Among authors: bosenberg m. Cancer Cell. 2015 Jan 12;27(1):41-56. doi: 10.1016/j.ccell.2014.11.014. Cancer Cell. 2015. PMID: 25584893 Free PMC article.
Amplification of CDK4 and MDM2 in malignant melanoma.
Muthusamy V, Hobbs C, Nogueira C, Cordon-Cardo C, McKee PH, Chin L, Bosenberg MW. Muthusamy V, et al. Genes Chromosomes Cancer. 2006 May;45(5):447-54. doi: 10.1002/gcc.20310. Genes Chromosomes Cancer. 2006. PMID: 16419059
Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
Dankort D, Curley DP, Cartlidge RA, Nelson B, Karnezis AN, Damsky WE Jr, You MJ, DePinho RA, McMahon M, Bosenberg M. Dankort D, et al. Among authors: bosenberg m. Nat Genet. 2009 May;41(5):544-52. doi: 10.1038/ng.356. Epub 2009 Mar 12. Nat Genet. 2009. PMID: 19282848 Free PMC article.
291 results