Verbist B - Search Results

1

Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project.

Verbist B, Klambauer G, Vervoort L, Talloen W; QSTAR Consortium; Shkedy Z, Thas O, Bender A, Göhlmann HW, Hochreiter S. Verbist B, et al. Drug Discov Today. 2015 May;20(5):505-13. doi: 10.1016/j.drudis.2014.12.014. Epub 2015 Jan 10. Drug Discov Today. 2015. PMID: 25582842 Free article.

2

VirVarSeq: a low-frequency virus variant detection pipeline for Illumina sequencing using adaptive base-calling accuracy filtering.

Verbist BM, Thys K, Reumers J, Wetzels Y, Van der Borght K, Talloen W, Aerssens J, Clement L, Thas O. Verbist BM, et al. Bioinformatics. 2015 Jan 1;31(1):94-101. doi: 10.1093/bioinformatics/btu587. Epub 2014 Aug 31. Bioinformatics. 2015. PMID: 25178459

3

Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.

Ravindranath AC, Perualila-Tan N, Kasim A, Drakakis G, Liggi S, Brewerton SC, Mason D, Bodkin MJ, Evans DA, Bhagwat A, Talloen W, Göhlmann HW, Shkedy Z, Bender A; QSTAR Consortium. Ravindranath AC, et al. Mol Biosyst. 2015 Jan;11(1):86-96. doi: 10.1039/c4mb00328d. Epub 2014 Sep 25. Mol Biosyst. 2015. PMID: 25254964

4

ViVaMBC: estimating viral sequence variation in complex populations from illumina deep-sequencing data using model-based clustering.

Verbist B, Clement L, Reumers J, Thys K, Vapirev A, Talloen W, Wetzels Y, Meys J, Aerssens J, Bijnens L, Thas O. Verbist B, et al. BMC Bioinformatics. 2015 Feb 22;16:59. doi: 10.1186/s12859-015-0458-7. BMC Bioinformatics. 2015. PMID: 25887734 Free PMC article.

5

Principal bicorrelation analysis: Unraveling associations between three data sources.

Mattiello F, Thas O, Verbist B. Mattiello F, et al. Among authors: verbist b. J Biopharm Stat. 2016;26(3):534-51. doi: 10.1080/10543406.2015.1052491. Epub 2015 Jun 22. J Biopharm Stat. 2016. PMID: 26098298

6

Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy.

Verbist BM, Verheyen GR, Vervoort L, Crabbe M, Beerens D, Bosmans C, Jaensch S, Osselaer S, Talloen W, Van den Wyngaert I, Van Hecke G, Wuyts D; QSTAR Consortium; Van Goethem F, Göhlmann HW. Verbist BM, et al. Chem Res Toxicol. 2015 Oct 19;28(10):1914-25. doi: 10.1021/acs.chemrestox.5b00103. Epub 2015 Sep 15. Chem Res Toxicol. 2015. PMID: 26313431 Free article.

7

A web application for sample size and power calculation in case-control microbiome studies.

Mattiello F, Verbist B, Faust K, Raes J, Shannon WD, Bijnens L, Thas O. Mattiello F, et al. Among authors: verbist b. Bioinformatics. 2016 Jul 1;32(13):2038-40. doi: 10.1093/bioinformatics/btw099. Epub 2016 Feb 19. Bioinformatics. 2016. PMID: 27153704

8

A joint modeling approach for uncovering associations between gene expression, bioactivity and chemical structure in early drug discovery to guide lead selection and genomic biomarker development.

Perualila-Tan N, Kasim A, Talloen W, Verbist B, Göhlmann HW; QSTAR Consortium; Shkedy Z. Perualila-Tan N, et al. Among authors: verbist b. Stat Appl Genet Mol Biol. 2016 Aug 1;15(4):291-304. doi: 10.1515/sagmb-2014-0086. Stat Appl Genet Mol Biol. 2016. PMID: 27269248

9

BIGL: Biochemically Intuitive Generalized Loewe null model for prediction of the expected combined effect compatible with partial agonism and antagonism.

Van der Borght K, Tourny A, Bagdziunas R, Thas O, Nazarov M, Turner H, Verbist B, Ceulemans H. Van der Borght K, et al. Among authors: verbist b. Sci Rep. 2017 Dec 20;7(1):17935. doi: 10.1038/s41598-017-18068-5. Sci Rep. 2017. PMID: 29263342 Free PMC article.

10

Statistical detection of synergy: New methods and a comparative study.

Thas O, Tourny A, Verbist B, Hawinkel S, Nazarov M, Mutambanengwe K, Bijnens L. Thas O, et al. Among authors: verbist b. Pharm Stat. 2022 Mar;21(2):345-360. doi: 10.1002/pst.2173. Epub 2021 Oct 4. Pharm Stat. 2022. PMID: 34608741

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