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Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.
Ravindranath AC, Perualila-Tan N, Kasim A, Drakakis G, Liggi S, Brewerton SC, Mason D, Bodkin MJ, Evans DA, Bhagwat A, Talloen W, Göhlmann HW, Shkedy Z, Bender A; QSTAR Consortium. Ravindranath AC, et al. Among authors: bender a. Mol Biosyst. 2015 Jan;11(1):86-96. doi: 10.1039/c4mb00328d. Epub 2014 Sep 25. Mol Biosyst. 2015. PMID: 25254964
DeepSynergy: predicting anti-cancer drug synergy with Deep Learning.
Preuer K, Lewis RPI, Hochreiter S, Bender A, Bulusu KC, Klambauer G. Preuer K, et al. Among authors: bender a. Bioinformatics. 2018 May 1;34(9):1538-1546. doi: 10.1093/bioinformatics/btx806. Bioinformatics. 2018. PMID: 29253077 Free PMC article.
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consortium; Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J. Menden MP, et al. Nat Commun. 2019 Jun 17;10(1):2674. doi: 10.1038/s41467-019-09799-2. Nat Commun. 2019. PMID: 31209238 Free PMC article.
1,343 results