Xu H - Search Results

1

The γ-secretase complex: from structure to function.

Zhang X, Li Y, Xu H, Zhang YW. Zhang X, et al. Among authors: xu h. Front Cell Neurosci. 2014 Dec 11;8:427. doi: 10.3389/fncel.2014.00427. eCollection 2014. Front Cell Neurosci. 2014. PMID: 25565961 Free PMC article. Review.

2

Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components.

Wang H, Luo WJ, Zhang YW, Li YM, Thinakaran G, Greengard P, Xu H. Wang H, et al. Among authors: xu h. J Biol Chem. 2004 Sep 24;279(39):40560-6. doi: 10.1074/jbc.M404345200. Epub 2004 Jul 7. J Biol Chem. 2004. PMID: 15247291 Free article.

3

Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.

Zhang YW, Luo WJ, Wang H, Lin P, Vetrivel KS, Liao F, Li F, Wong PC, Farquhar MG, Thinakaran G, Xu H. Zhang YW, et al. Among authors: xu h. J Biol Chem. 2005 Apr 29;280(17):17020-6. doi: 10.1074/jbc.M409467200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15711015 Free PMC article.

4

Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation.

Han P, Dou F, Li F, Zhang X, Zhang YW, Zheng H, Lipton SA, Xu H, Liao FF. Han P, et al. Among authors: xu h. J Neurosci. 2005 Dec 14;25(50):11542-52. doi: 10.1523/JNEUROSCI.3831-05.2005. J Neurosci. 2005. PMID: 16354912 Free PMC article.

5

Transcriptional regulation of PEN-2, a key component of the gamma-secretase complex, by CREB.

Wang R, Zhang YW, Sun P, Liu R, Zhang X, Zhang X, Xia K, Xia J, Xu H, Zhang Z. Wang R, et al. Among authors: xu h. Mol Cell Biol. 2006 Feb;26(4):1347-54. doi: 10.1128/MCB.26.4.1347-1354.2006. Mol Cell Biol. 2006. PMID: 16449647 Free PMC article.

6

Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia.

Wang R, Zhang YW, Zhang X, Liu R, Zhang X, Hong S, Xia K, Xia J, Zhang Z, Xu H. Wang R, et al. Among authors: xu h. FASEB J. 2006 Jun;20(8):1275-7. doi: 10.1096/fj.06-5839fje. Epub 2006 Apr 27. FASEB J. 2006. PMID: 16645044

7

Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubules.

Zhang X, Li F, Bulloj A, Zhang YW, Tong G, Zhang Z, Liao FF, Xu H. Zhang X, et al. Among authors: xu h. FASEB J. 2006 Jun;20(8):1272-4. doi: 10.1096/fj.06-5721fje. Epub 2006 Apr 27. FASEB J. 2006. PMID: 16645045

8

Pathological and physiological functions of presenilins.

Vetrivel KS, Zhang YW, Xu H, Thinakaran G. Vetrivel KS, et al. Among authors: xu h. Mol Neurodegener. 2006 Jun 12;1:4. doi: 10.1186/1750-1326-1-4. Mol Neurodegener. 2006. PMID: 16930451 Free PMC article.

9

Tumor suppressor PTEN affects tau phosphorylation: deficiency in the phosphatase activity of PTEN increases aggregation of an FTDP-17 mutant Tau.

Zhang X, Zhang YW, Liu S, Bulloj A, Tong GG, Zhang Z, Liao FF, Xu H. Zhang X, et al. Among authors: xu h. Mol Neurodegener. 2006 Jul 31;1:7. doi: 10.1186/1750-1326-1-7. Mol Neurodegener. 2006. PMID: 16930454 Free PMC article.

10

Presenilins regulate the cellular level of the tumor suppressor PTEN.

Zhang H, Liu R, Wang R, Hong S, Xu H, Zhang YW. Zhang H, et al. Among authors: xu h. Neurobiol Aging. 2008 May;29(5):653-60. doi: 10.1016/j.neurobiolaging.2006.11.020. Epub 2007 Jan 12. Neurobiol Aging. 2008. PMID: 17222949 Free PMC article.

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