Margolis BL - Search Results

1

Phospholipase C-gamma, a substrate for PDGF receptor kinase, is not phosphorylated on tyrosine during the mitogenic response to CSF-1.

Downing JR, Margolis BL, Zilberstein A, Ashmun RA, Ullrich A, Sherr CJ, Schlessinger J. Downing JR, et al. Among authors: margolis bl. EMBO J. 1989 Nov;8(11):3345-50. doi: 10.1002/j.1460-2075.1989.tb08496.x. EMBO J. 1989. PMID: 2555162 Free PMC article.

2

The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma.

Margolis B, Li N, Koch A, Mohammadi M, Hurwitz DR, Zilberstein A, Ullrich A, Pawson T, Schlessinger J. Margolis B, et al. EMBO J. 1990 Dec;9(13):4375-80. doi: 10.1002/j.1460-2075.1990.tb07887.x. EMBO J. 1990. PMID: 2176151 Free PMC article.

3

SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma.

Rotin D, Margolis B, Mohammadi M, Daly RJ, Daum G, Li N, Fischer EH, Burgess WH, Ullrich A, Schlessinger J. Rotin D, et al. EMBO J. 1992 Feb;11(2):559-67. doi: 10.1002/j.1460-2075.1992.tb05087.x. EMBO J. 1992. PMID: 1537335 Free PMC article.

4

PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

Kim HK, Kim JW, Zilberstein A, Margolis B, Kim JG, Schlessinger J, Rhee SG. Kim HK, et al. Cell. 1991 May 3;65(3):435-41. doi: 10.1016/0092-8674(91)90461-7. Cell. 1991. PMID: 1708307

5

Tyrosine kinase activity is essential for the association of phospholipase C-gamma with the epidermal growth factor receptor.

Margolis B, Bellot F, Honegger AM, Ullrich A, Schlessinger J, Zilberstein A. Margolis B, et al. Mol Cell Biol. 1990 Feb;10(2):435-41. doi: 10.1128/mcb.10.2.435-441.1990. Mol Cell Biol. 1990. PMID: 2153914 Free PMC article.

6

Effect of phospholipase C-gamma overexpression on PDGF-induced second messengers and mitogenesis.

Margolis B, Zilberstein A, Franks C, Felder S, Kremer S, Ullrich A, Rhee SG, Skorecki K, Schlessinger J. Margolis B, et al. Science. 1990 May 4;248(4955):607-10. doi: 10.1126/science.2333512. Science. 1990. PMID: 2333512

7

EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling.

Margolis B, Rhee SG, Felder S, Mervic M, Lyall R, Levitzki A, Ullrich A, Zilberstein A, Schlessinger J. Margolis B, et al. Cell. 1989 Jun 30;57(7):1101-7. doi: 10.1016/0092-8674(89)90047-0. Cell. 1989. PMID: 2472218

8

Presence of SH2 domains of phospholipase C gamma 1 enhances substrate phosphorylation by increasing the affinity toward the epidermal growth factor receptor.

Rotin D, Honegger AM, Margolis BL, Ullrich A, Schlessinger J. Rotin D, et al. Among authors: margolis bl. J Biol Chem. 1992 May 15;267(14):9678-83. J Biol Chem. 1992. PMID: 1315766 Free article.

9

Modified kinetics of platelet-derived growth factor-induced Ca2+ increases in NIH-3T3 cells overexpressing phospholipase C gamma 1.

Renard DC, Bolton MM, Rhee SG, Margolis BL, Zilberstein A, Schlessinger J, Thomas AP. Renard DC, et al. Among authors: margolis bl. Biochem J. 1992 Feb 1;281 ( Pt 3)(Pt 3):775-84. doi: 10.1042/bj2810775. Biochem J. 1992. PMID: 1536654 Free PMC article.

10

Distinct structural specificities for functional coupling of the epidermal growth factor receptor to calcium-signalling versus phospholipase A2 responses.

Hack N, Margolis BL, Ullrich A, Schlessinger J, Skorecki KL. Hack N, et al. Among authors: margolis bl. Biochem J. 1991 May 1;275 ( Pt 3)(Pt 3):563-7. doi: 10.1042/bj2750563. Biochem J. 1991. PMID: 1903921 Free PMC article.

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