Eklund CR - Search Results

1

Improving in vitro to in vivo extrapolation by incorporating toxicokinetic measurements: a case study of lindane-induced neurotoxicity.

Croom EL, Shafer TJ, Evans MV, Mundy WR, Eklund CR, Johnstone AF, Mack CM, Pegram RA. Croom EL, et al. Among authors: eklund cr. Toxicol Appl Pharmacol. 2015 Feb 15;283(1):9-19. doi: 10.1016/j.taap.2014.11.006. Epub 2014 Dec 18. Toxicol Appl Pharmacol. 2015. PMID: 25529470

2

Development of a human physiologically based pharmacokinetic (PBPK) model for dermal permeability for lindane.

Sawyer ME, Evans MV, Wilson CA, Beesley LJ, Leon LS, Eklund CR, Croom EL, Pegram RA. Sawyer ME, et al. Among authors: eklund cr. Toxicol Lett. 2016 Mar 14;245:106-9. doi: 10.1016/j.toxlet.2016.01.008. Epub 2016 Jan 18. Toxicol Lett. 2016. PMID: 26794662

3

The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM).

Kenyon EM, Eklund C, Lipscomb JC, Pegram RA. Kenyon EM, et al. Toxicol Mech Methods. 2016 Oct;26(8):620-626. doi: 10.1080/15376516.2016.1225141. Epub 2016 Oct 27. Toxicol Mech Methods. 2016. PMID: 27595344

4

Global optimization of the Michaelis-Menten parameters using physiologically-based pharmacokinetic (PBPK) modeling and chloroform vapor uptake data in F344 rats.

Evans MV, Eklund CR, Williams DN, Sey YM, Simmons JE. Evans MV, et al. Among authors: eklund cr. Inhal Toxicol. 2020 Feb;32(3):97-109. doi: 10.1080/08958378.2020.1742818. Epub 2020 Apr 2. Inhal Toxicol. 2020. PMID: 32241199 Free PMC article.

5

Duration adjustment of acute exposure guideline level values for trichloroethylene using a physiologically-based pharmacokinetic model.

Boyes WK, Evans MV, Eklund C, Janssen P, Simmons JE. Boyes WK, et al. Risk Anal. 2005 Jun;25(3):677-86. doi: 10.1111/j.1539-6924.2005.00622.x. Risk Anal. 2005. PMID: 16022699

6

Developing an exposure-dose-response model for the acute neurotoxicity of organic solvents: overview and progress on in vitro models and dosimetry.

Bushnell PJ, Shafer TJ, Bale AS, Boyes WK, Simmons JE, Eklund C, Jackson TL. Bushnell PJ, et al. Environ Toxicol Pharmacol. 2005 May;19(3):607-14. doi: 10.1016/j.etap.2004.12.026. Environ Toxicol Pharmacol. 2005. PMID: 21783533

7

Development and application of a human PBPK model for bromodichloromethane to investigate the impacts of multi-route exposure.

Kenyon EM, Eklund C, Leavens T, Pegram RA. Kenyon EM, et al. J Appl Toxicol. 2016 Sep;36(9):1095-111. doi: 10.1002/jat.3269. Epub 2015 Dec 9. J Appl Toxicol. 2016. PMID: 26649444

8

Comparison of in vivo derived and scaled in vitro metabolic rate constants for several volatile organic compounds (VOCs).

Kenyon EM, Eklund C, Pegram RA, Lipscomb JC. Kenyon EM, et al. Toxicol In Vitro. 2020 Dec;69:105002. doi: 10.1016/j.tiv.2020.105002. Epub 2020 Sep 15. Toxicol In Vitro. 2020. PMID: 32946980 Free PMC article.

9

Corrigendum to 'Comparison of In Vivo Derived and Scaled In Vitro Metabolic Rate Constants for Several Volatile Organic Compounds (VOCs)' [toxicology in vitro 68 (2020) start page-end page].

Kenyon EM, Eklund C, Pegram RA, Lipscomb JC. Kenyon EM, et al. Toxicol In Vitro. 2021 Sep;75:105045. doi: 10.1016/j.tiv.2020.105045. Epub 2020 Nov 5. Toxicol In Vitro. 2021. PMID: 33160764 No abstract available.

10

Physiologically Based Pharmacokinetic (PBPK) Modeling of Metabolic Pathways of Bromochloromethane in Rats.

Cuello WS, Janes TA, Jessee JM, Venecek MA, Sawyer ME, Eklund CR, Evans MV. Cuello WS, et al. Among authors: eklund cr. J Toxicol. 2012;2012:629781. doi: 10.1155/2012/629781. Epub 2012 Apr 11. J Toxicol. 2012. PMID: 22719758 Free PMC article.

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