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HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.
Rai TS, Cole JJ, Nelson DM, Dikovskaya D, Faller WJ, Vizioli MG, Hewitt RN, Anannya O, McBryan T, Manoharan I, van Tuyn J, Morrice N, Pchelintsev NA, Ivanov A, Brock C, Drotar ME, Nixon C, Clark W, Sansom OJ, Anderson KI, King A, Blyth K, Adams PD. Rai TS, et al. Among authors: morrice n. Genes Dev. 2014 Dec 15;28(24):2712-25. doi: 10.1101/gad.247528.114. Genes Dev. 2014. PMID: 25512559 Free PMC article.
Fumarate induces redox-dependent senescence by modifying glutathione metabolism.
Zheng L, Cardaci S, Jerby L, MacKenzie ED, Sciacovelli M, Johnson TI, Gaude E, King A, Leach JD, Edrada-Ebel R, Hedley A, Morrice NA, Kalna G, Blyth K, Ruppin E, Frezza C, Gottlieb E. Zheng L, et al. Nat Commun. 2015 Jan 23;6:6001. doi: 10.1038/ncomms7001. Nat Commun. 2015. PMID: 25613188 Free PMC article.
Blebs produced by actin-myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs.
Wickman GR, Julian L, Mardilovich K, Schumacher S, Munro J, Rath N, Zander SA, Mleczak A, Sumpton D, Morrice N, Bienvenut WV, Olson MF. Wickman GR, et al. Among authors: morrice n. Cell Death Differ. 2013 Oct;20(10):1293-305. doi: 10.1038/cdd.2013.69. Epub 2013 Jun 21. Cell Death Differ. 2013. PMID: 23787996 Free PMC article.
LPP3 mediates self-generation of chemotactic LPA gradients by melanoma cells.
Susanto O, Koh YWH, Morrice N, Tumanov S, Thomason PA, Nielson M, Tweedy L, Muinonen-Martin AJ, Kamphorst JJ, Mackay GM, Insall RH. Susanto O, et al. Among authors: morrice n. J Cell Sci. 2017 Oct 15;130(20):3455-3466. doi: 10.1242/jcs.207514. Epub 2017 Sep 4. J Cell Sci. 2017. PMID: 28871044 Free PMC article.
220 results