Adams PD - Search Results

1

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.

Rai TS, Cole JJ, Nelson DM, Dikovskaya D, Faller WJ, Vizioli MG, Hewitt RN, Anannya O, McBryan T, Manoharan I, van Tuyn J, Morrice N, Pchelintsev NA, Ivanov A, Brock C, Drotar ME, Nixon C, Clark W, Sansom OJ, Anderson KI, King A, Blyth K, Adams PD. Rai TS, et al. Among authors: adams pd. Genes Dev. 2014 Dec 15;28(24):2712-25. doi: 10.1101/gad.247528.114. Genes Dev. 2014. PMID: 25512559 Free PMC article.

2

Coupling of DNA synthesis and histone synthesis in S phase independent of cyclin/cdk2 activity.

Nelson DM, Ye X, Hall C, Santos H, Ma T, Kao GD, Yen TJ, Harper JW, Adams PD. Nelson DM, et al. Among authors: adams pd. Mol Cell Biol. 2002 Nov;22(21):7459-72. doi: 10.1128/MCB.22.21.7459-7472.2002. Mol Cell Biol. 2002. PMID: 12370293 Free PMC article.

3

Defective S phase chromatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest.

Ye X, Franco AA, Santos H, Nelson DM, Kaufman PD, Adams PD. Ye X, et al. Among authors: adams pd. Mol Cell. 2003 Feb;11(2):341-51. doi: 10.1016/s1097-2765(03)00037-6. Mol Cell. 2003. PMID: 12620223 Free article.

4

Biochemical analysis of the cell cycle and cell cycle checkpoints in transiently transfected cells after collection with magnetic beads.

Ye X, Poustovoitov M, Santos H, Nelson DM, Adams PD. Ye X, et al. Among authors: adams pd. Methods Mol Biol. 2004;281:261-70. doi: 10.1385/1-59259-811-0:261. Methods Mol Biol. 2004. PMID: 15220535

5

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA.

Zhang R, Poustovoitov MV, Ye X, Santos HA, Chen W, Daganzo SM, Erzberger JP, Serebriiskii IG, Canutescu AA, Dunbrack RL, Pehrson JR, Berger JM, Kaufman PD, Adams PD. Zhang R, et al. Among authors: adams pd. Dev Cell. 2005 Jan;8(1):19-30. doi: 10.1016/j.devcel.2004.10.019. Dev Cell. 2005. PMID: 15621527 Free article.

6

Remodeling chromatin for senescence.

Adams PD. Adams PD. Aging Cell. 2007 Aug;6(4):425-7. doi: 10.1111/j.1474-9726.2007.00313.x. Aging Cell. 2007. PMID: 17635419 Free article.

7

Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence.

Adams PD. Adams PD. Mol Cell. 2009 Oct 9;36(1):2-14. doi: 10.1016/j.molcel.2009.09.021. Mol Cell. 2009. PMID: 19818705 Free article. Review.

8

Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci.

Kennedy AL, McBryan T, Enders GH, Johnson FB, Zhang R, Adams PD. Kennedy AL, et al. Among authors: adams pd. Cell Div. 2010 Jun 22;5:16. doi: 10.1186/1747-1028-5-16. Cell Div. 2010. PMID: 20569479 Free PMC article.

9

Chromatin: a molecular interface between cancer and aging.

Cruickshanks HA, Adams PD. Cruickshanks HA, et al. Among authors: adams pd. Curr Opin Genet Dev. 2011 Feb;21(1):100-6. doi: 10.1016/j.gde.2010.10.007. Epub 2010 Nov 17. Curr Opin Genet Dev. 2011. PMID: 21087854 Free PMC article. Review.

10

Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis.

Kennedy AL, Morton JP, Manoharan I, Nelson DM, Jamieson NB, Pawlikowski JS, McBryan T, Doyle B, McKay C, Oien KA, Enders GH, Zhang R, Sansom OJ, Adams PD. Kennedy AL, et al. Among authors: adams pd. Mol Cell. 2011 Apr 8;42(1):36-49. doi: 10.1016/j.molcel.2011.02.020. Mol Cell. 2011. PMID: 21474066 Free PMC article.

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