Derks IA - Search Results

1

Induction of TAp73 by platinum-based compounds to overcome drug resistance in p53 dysfunctional chronic lymphocytic leukemia.

Tonino SH, Mulkens CE, van Laar J, Derks IA, Suo G, Croon-de Boer F, van Oers MH, Eldering E, Wang JY, Kater AP. Tonino SH, et al. Among authors: derks ia. Leuk Lymphoma. 2015;56(8):2439-47. doi: 10.3109/10428194.2014.996751. Epub 2015 Jan 21. Leuk Lymphoma. 2015. PMID: 25511680 Free PMC article.

2

Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways.

Eldering E, Spek CA, Aberson HL, Grummels A, Derks IA, de Vos AF, McElgunn CJ, Schouten JP. Eldering E, et al. Among authors: derks ia. Nucleic Acids Res. 2003 Dec 1;31(23):e153. doi: 10.1093/nar/gng153. Nucleic Acids Res. 2003. PMID: 14627843 Free PMC article.

3

Apoptosis via the B cell antigen receptor requires Bax translocation and involves mitochondrial depolarization, cytochrome C release, and caspase-9 activation.

Eldering E, Mackus WJ, Derks IA, Evers LM, Beuling E, Teeling P, Lens SM, van Oers MH, van Lier RA. Eldering E, et al. Among authors: derks ia. Eur J Immunol. 2004 Jul;34(7):1950-60. doi: 10.1002/eji.200324817. Eur J Immunol. 2004. PMID: 15214043 Free article.

4

The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells.

Alves NL, Derks IAM, Berk E, Spijker R, van Lier RAW, Eldering E. Alves NL, et al. Immunity. 2006 Jun;24(6):703-716. doi: 10.1016/j.immuni.2006.03.018. Immunity. 2006. PMID: 16782027 Free article.

5

Crosstalk among Bcl-2 family members in B-CLL: seliciclib acts via the Mcl-1/Noxa axis and gradual exhaustion of Bcl-2 protection.

Hallaert DY, Spijker R, Jak M, Derks IA, Alves NL, Wensveen FM, de Boer JP, de Jong D, Green SR, van Oers MH, Eldering E. Hallaert DY, et al. Among authors: derks ia. Cell Death Differ. 2007 Nov;14(11):1958-67. doi: 10.1038/sj.cdd.4402211. Epub 2007 Aug 17. Cell Death Differ. 2007. PMID: 17703234

6

CD20 deficiency in humans results in impaired T cell-independent antibody responses.

Kuijpers TW, Bende RJ, Baars PA, Grummels A, Derks IA, Dolman KM, Beaumont T, Tedder TF, van Noesel CJ, Eldering E, van Lier RA. Kuijpers TW, et al. Among authors: derks ia. J Clin Invest. 2010 Jan;120(1):214-22. doi: 10.1172/JCI40231. Epub 2009 Dec 21. J Clin Invest. 2010. PMID: 20038800 Free PMC article.

7

Apoptosis threshold set by Noxa and Mcl-1 after T cell activation regulates competitive selection of high-affinity clones.

Wensveen FM, van Gisbergen KP, Derks IA, Gerlach C, Schumacher TN, van Lier RA, Eldering E. Wensveen FM, et al. Among authors: derks ia. Immunity. 2010 Jun 25;32(6):754-65. doi: 10.1016/j.immuni.2010.06.005. Immunity. 2010. PMID: 20620942 Free article.

8

Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1.

Wensveen FM, Alves NL, Derks IA, Reedquist KA, Eldering E. Wensveen FM, et al. Among authors: derks ia. Apoptosis. 2011 Jul;16(7):708-21. doi: 10.1007/s10495-011-0599-8. Apoptosis. 2011. PMID: 21516346 Free PMC article.

9

BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation.

Wensveen FM, Derks IA, van Gisbergen KP, de Bruin AM, Meijers JC, Yigittop H, Nolte MA, Eldering E, van Lier RA. Wensveen FM, et al. Among authors: derks ia. Blood. 2012 Feb 9;119(6):1440-9. doi: 10.1182/blood-2011-09-378877. Epub 2011 Dec 5. Blood. 2012. PMID: 22144184 Free article.

10

CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

Wensveen FM, Unger PP, Kragten NA, Derks IA, ten Brinke A, Arens R, van Lier RA, Eldering E, van Gisbergen KP. Wensveen FM, et al. Among authors: derks ia. J Immunol. 2012 May 1;188(9):4256-67. doi: 10.4049/jimmunol.1102889. Epub 2012 Mar 26. J Immunol. 2012. PMID: 22450812

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