Ousterout DG - Search Results

1

Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.

Ousterout DG, Kabadi AM, Thakore PI, Perez-Pinera P, Brown MT, Majoros WH, Reddy TE, Gersbach CA. Ousterout DG, et al. Mol Ther. 2015 Mar;23(3):523-32. doi: 10.1038/mt.2014.234. Epub 2014 Dec 10. Mol Ther. 2015. PMID: 25492562 Free PMC article.

2

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases.

Perez-Pinera P, Ousterout DG, Brown MT, Gersbach CA. Perez-Pinera P, et al. Among authors: ousterout dg. Nucleic Acids Res. 2012 Apr;40(8):3741-52. doi: 10.1093/nar/gkr1214. Epub 2011 Dec 14. Nucleic Acids Res. 2012. PMID: 22169954 Free PMC article.

3

Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

Ousterout DG, Perez-Pinera P, Thakore PI, Kabadi AM, Brown MT, Qin X, Fedrigo O, Mouly V, Tremblay JP, Gersbach CA. Ousterout DG, et al. Mol Ther. 2013 Sep;21(9):1718-26. doi: 10.1038/mt.2013.111. Epub 2013 Jun 4. Mol Ther. 2013. PMID: 23732986 Free PMC article.

4

Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.

Ousterout DG, Kabadi AM, Thakore PI, Majoros WH, Reddy TE, Gersbach CA. Ousterout DG, et al. Nat Commun. 2015 Feb 18;6:6244. doi: 10.1038/ncomms7244. Nat Commun. 2015. PMID: 25692716 Free PMC article.

5

The Development of TALE Nucleases for Biotechnology.

Ousterout DG, Gersbach CA. Ousterout DG, et al. Methods Mol Biol. 2016;1338:27-42. doi: 10.1007/978-1-4939-2932-0_3. Methods Mol Biol. 2016. PMID: 26443211 Free PMC article.

6

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. Nelson CE, et al. Among authors: ousterout dg. Science. 2016 Jan 22;351(6271):403-7. doi: 10.1126/science.aad5143. Epub 2015 Dec 31. Science. 2016. PMID: 26721684 Free PMC article.

7

Advances in targeted genome editing.

Perez-Pinera P, Ousterout DG, Gersbach CA. Perez-Pinera P, et al. Among authors: ousterout dg. Curr Opin Chem Biol. 2012 Aug;16(3-4):268-77. doi: 10.1016/j.cbpa.2012.06.007. Epub 2012 Jul 20. Curr Opin Chem Biol. 2012. PMID: 22819644 Free PMC article. Review.

8

RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA. Perez-Pinera P, et al. Among authors: ousterout dg. Nat Methods. 2013 Oct;10(10):973-6. doi: 10.1038/nmeth.2600. Epub 2013 Jul 25. Nat Methods. 2013. PMID: 23892895 Free PMC article.

9

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector.

Kabadi AM, Ousterout DG, Hilton IB, Gersbach CA. Kabadi AM, et al. Among authors: ousterout dg. Nucleic Acids Res. 2014 Oct 29;42(19):e147. doi: 10.1093/nar/gku749. Epub 2014 Aug 13. Nucleic Acids Res. 2014. PMID: 25122746 Free PMC article.

10

Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain.

Kabadi AM, Thakore PI, Vockley CM, Ousterout DG, Gibson TM, Guilak F, Reddy TE, Gersbach CA. Kabadi AM, et al. Among authors: ousterout dg. ACS Synth Biol. 2015 Jun 19;4(6):689-99. doi: 10.1021/sb500322u. Epub 2014 Dec 31. ACS Synth Biol. 2015. PMID: 25494287 Free PMC article.

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