Yang Z - Search Results

1

Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).

Xu JG, Huang C, Yang Z, Jin M, Fu P, Zhang N, Luo J, Li D, Liu M, Zhou Y, Zhu Y. Xu JG, et al. Among authors: yang z. J Biol Chem. 2015 Jan 23;290(4):2455-65. doi: 10.1074/jbc.M114.599134. Epub 2014 Dec 5. J Biol Chem. 2015. PMID: 25480784 Free PMC article.

2

LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.

Yue Z, Yuan Z, Zeng L, Wang Y, Lai L, Li J, Sun P, Xue X, Qi J, Yang Z, Zheng Y, Fang Y, Li D, Siwko S, Li Y, Luo J, Liu M. Yue Z, et al. Among authors: yang z. FASEB J. 2018 May;32(5):2422-2437. doi: 10.1096/fj.201700897R. Epub 2017 Dec 21. FASEB J. 2018. PMID: 29269400 Free PMC article.

Our findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast CSCs.-Yue, Z., Yuan, Z., Zeng, L., Wang, Y., Lai, L., Li, J., Sun, P., Xue, X., Qi, J., Yang, Z., Zheng, Y., Fang, Y., Li, D., S …

Our findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast CSCs.-Yue, Z …

3

Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β signaling pathway.

Zheng C, Fang Y, Tong W, Li G, Wu H, Zhou W, Lin Q, Yang F, Yang Z, Wang P, Peng Y, Pang X, Yi Z, Luo J, Liu M, Chen Y. Zheng C, et al. Among authors: yang f, yang z. J Med Chem. 2014 Feb 13;57(3):600-12. doi: 10.1021/jm401117t. Epub 2014 Jan 27. J Med Chem. 2014. PMID: 24417479

4

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.

Luo J, Yang Z, Ma Y, Yue Z, Lin H, Qu G, Huang J, Dai W, Li C, Zheng C, Xu L, Chen H, Wang J, Li D, Siwko S, Penninger JM, Ning G, Xiao J, Liu M. Luo J, et al. Among authors: yang z. Nat Med. 2016 May;22(5):539-46. doi: 10.1038/nm.4076. Epub 2016 Apr 11. Nat Med. 2016. PMID: 27064449

5

Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.

Yang Z, Li C, Wang X, Zhai C, Yi Z, Wang L, Liu B, Du B, Wu H, Guo X, Liu M, Li D, Luo J. Yang Z, et al. J Cell Physiol. 2010 Oct;225(1):266-75. doi: 10.1002/jcp.22261. J Cell Physiol. 2010. PMID: 20509140

6

Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways.

Li C, Yang Z, Li Z, Ma Y, Zhang L, Zheng C, Qiu W, Wu X, Wang X, Li H, Tang J, Qian M, Li D, Wang P, Luo J, Liu M. Li C, et al. Among authors: yang z. J Bone Miner Res. 2011 Mar;26(3):644-56. doi: 10.1002/jbmr.242. J Bone Miner Res. 2011. PMID: 20814972 Free article.

7

RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis.

Yue Z, Niu X, Yuan Z, Qin Q, Jiang W, He L, Gao J, Ding Y, Liu Y, Xu Z, Li Z, Yang Z, Li R, Xue X, Gao Y, Yue F, Zhang XH, Hu G, Wang Y, Li Y, Chen G, Siwko S, Gartland A, Wang N, Xiao J, Liu M, Luo J. Yue Z, et al. Among authors: yang z. J Clin Invest. 2022 Jan 18;132(2):e144579. doi: 10.1172/JCI144579. J Clin Invest. 2022. PMID: 34847079 Free PMC article.

8

Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway.

Li C, Yang Z, Zhai C, Qiu W, Li D, Yi Z, Wang L, Tang J, Qian M, Luo J, Liu M. Li C, et al. Among authors: yang z. Mol Cancer. 2010 Apr 6;9:73. doi: 10.1186/1476-4598-9-73. Mol Cancer. 2010. PMID: 20367887 Free PMC article.

9

Stereoselective synthesis of some methyl-substituted steroid hormones and their in vitro cytotoxic activity against human gastric cancer cell line MGC-803.

Li C, Qiu W, Yang Z, Luo J, Yang F, Liu M, Xie J, Tang J. Li C, et al. Among authors: yang f, yang z. Steroids. 2010 Dec;75(12):859-69. doi: 10.1016/j.steroids.2010.05.008. Epub 2010 May 21. Steroids. 2010. PMID: 20493894

10

Bortezomib Inhibits Giant Cell Tumor of Bone through Induction of Cell Apoptosis and Inhibition of Osteoclast Recruitment, Giant Cell Formation, and Bone Resorption.

Xu L, Luo J, Jin R, Yue Z, Sun P, Yang Z, Yang X, Wan W, Zhang J, Li S, Liu M, Xiao J. Xu L, et al. Among authors: yang x, yang z. Mol Cancer Ther. 2016 May;15(5):854-65. doi: 10.1158/1535-7163.MCT-15-0669. Epub 2016 Feb 9. Mol Cancer Ther. 2016. PMID: 26861247

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