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Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment.
Ranganath LR, Milan AM, Hughes AT, Dutton JJ, Fitzgerald R, Briggs MC, Bygott H, Psarelli EE, Cox TF, Gallagher JA, Jarvis JC, van Kan C, Hall AK, Laan D, Olsson B, Szamosi J, Rudebeck M, Kullenberg T, Cronlund A, Svensson L, Junestrand C, Ayoob H, Timmis OG, Sireau N, Le Quan Sang KH, Genovese F, Braconi D, Santucci A, Nemethova M, Zatkova A, McCaffrey J, Christensen P, Ross G, Imrich R, Rovensky J. Ranganath LR, et al. Ann Rheum Dis. 2016 Feb;75(2):362-7. doi: 10.1136/annrheumdis-2014-206033. Epub 2014 Dec 4. Ann Rheum Dis. 2016. PMID: 25475116 Clinical Trial.
Alkaptonuria--a review of surgical and autopsy pathology.
Helliwell TR, Gallagher JA, Ranganath L. Helliwell TR, et al. Histopathology. 2008 Nov;53(5):503-12. doi: 10.1111/j.1365-2559.2008.03000.x. Epub 2008 Mar 8. Histopathology. 2008. PMID: 18336562 Review.
Development of an in vitro model to investigate joint ochronosis in alkaptonuria.
Tinti L, Taylor AM, Santucci A, Wlodarski B, Wilson PJ, Jarvis JC, Fraser WD, Davidson JS, Ranganath LR, Gallagher JA. Tinti L, et al. Among authors: ranganath lr. Rheumatology (Oxford). 2011 Feb;50(2):271-7. doi: 10.1093/rheumatology/keq246. Epub 2010 Oct 15. Rheumatology (Oxford). 2011. PMID: 20952450
Cardiovascular manifestations of Alkaptonuria.
Pettit SJ, Fisher M, Gallagher JA, Ranganath LR. Pettit SJ, et al. Among authors: ranganath lr. J Inherit Metab Dis. 2011 Dec;34(6):1177-81. doi: 10.1007/s10545-011-9339-z. Epub 2011 Apr 20. J Inherit Metab Dis. 2011. PMID: 21506017
Living with alkaptonuria.
Laxon S, Ranganath L, Timmis O. Laxon S, et al. BMJ. 2011 Sep 29;343:d5155. doi: 10.1136/bmj.d5155. BMJ. 2011. PMID: 21964346 No abstract available.
157 results