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Page 1
Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression.
Weiss A, Träger U, Wild EJ, Grueninger S, Farmer R, Landles C, Scahill RI, Lahiri N, Haider S, Macdonald D, Frost C, Bates GP, Bilbe G, Kuhn R, Andre R, Tabrizi SJ. Weiss A, et al. Among authors: trager u. J Clin Invest. 2012 Oct;122(10):3731-6. doi: 10.1172/JCI64565. Epub 2012 Sep 17. J Clin Invest. 2012. PMID: 22996692 Free PMC article.
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation.
Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Björkqvist M, Ostroff GR, Aronin N, Tabrizi SJ. Träger U, et al. Brain. 2014 Mar;137(Pt 3):819-33. doi: 10.1093/brain/awt355. Epub 2014 Jan 22. Brain. 2014. PMID: 24459107 Free PMC article.
Mutant huntingtin impairs immune cell migration in Huntington disease.
Kwan W, Träger U, Davalos D, Chou A, Bouchard J, Andre R, Miller A, Weiss A, Giorgini F, Cheah C, Möller T, Stella N, Akassoglou K, Tabrizi SJ, Muchowski PJ. Kwan W, et al. Among authors: trager u. J Clin Invest. 2012 Dec;122(12):4737-47. doi: 10.1172/JCI64484. Epub 2012 Nov 19. J Clin Invest. 2012. PMID: 23160193 Free PMC article.
Peripheral inflammation in neurodegeneration.
Träger U, Tabrizi SJ. Träger U, et al. J Mol Med (Berl). 2013 Jun;91(6):673-81. doi: 10.1007/s00109-013-1026-0. Epub 2013 Apr 2. J Mol Med (Berl). 2013. PMID: 23546523 Review.
JAK/STAT Signalling in Huntington's Disease Immune Cells.
Träger U, Magnusson A, Lahiri Swales N, Wild E, North J, Lowdell M, Björkqvist M. Träger U, et al. PLoS Curr. 2013 Dec 13;5:ecurrents.hd.5791c897b5c3bebeed93b1d1da0c0648. doi: 10.1371/currents.hd.5791c897b5c3bebeed93b1d1da0c0648. PLoS Curr. 2013. PMID: 24459609 Free PMC article.
19 results