Shum MS - Search Results

1

TUBB3/βIII-tubulin acts through the PTEN/AKT signaling axis to promote tumorigenesis and anoikis resistance in non-small cell lung cancer.

McCarroll JA, Gan PP, Erlich RB, Liu M, Dwarte T, Sagnella SS, Akerfeldt MC, Yang L, Parker AL, Chang MH, Shum MS, Byrne FL, Kavallaris M. McCarroll JA, et al. Among authors: shum ms. Cancer Res. 2015 Jan 15;75(2):415-25. doi: 10.1158/0008-5472.CAN-14-2740. Epub 2014 Nov 20. Cancer Res. 2015. PMID: 25414139

2

γ-Actin regulates cell migration and modulates the ROCK signaling pathway.

Shum MS, Pasquier E, Po'uha ST, O'Neill GM, Chaponnier C, Gunning PW, Kavallaris M. Shum MS, et al. FASEB J. 2011 Dec;25(12):4423-33. doi: 10.1096/fj.11-185447. Epub 2011 Sep 9. FASEB J. 2011. PMID: 21908715

3

LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs.

Po'uha ST, Shum MS, Goebel A, Bernard O, Kavallaris M. Po'uha ST, et al. Among authors: shum ms. Oncogene. 2010 Jan 28;29(4):597-607. doi: 10.1038/onc.2009.367. Epub 2009 Nov 2. Oncogene. 2010. PMID: 19881550

4

Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma.

Cheung BB, Tan O, Koach J, Liu B, Shum MS, Carter DR, Sutton S, Po'uha ST, Chesler L, Haber M, Norris MD, Kavallaris M, Liu T, O'Neill GM, Marshall GM. Cheung BB, et al. Among authors: shum ms. Mol Oncol. 2015 Aug;9(7):1484-500. doi: 10.1016/j.molonc.2015.04.005. Epub 2015 Apr 29. Mol Oncol. 2015. PMID: 25963741 Free PMC article.

5

NEDD9 regulates 3D migratory activity independent of the Rac1 morphology switch in glioma and neuroblastoma.

Zhong J, Bach CT, Shum MS, O'Neill GM. Zhong J, et al. Among authors: shum ms. Mol Cancer Res. 2014 Feb;12(2):264-73. doi: 10.1158/1541-7786.MCR-13-0513. Epub 2013 Dec 13. Mol Cancer Res. 2014. PMID: 24337070

6

AMPK in skeletal muscle function and metabolism.

Kjøbsted R, Hingst JR, Fentz J, Foretz M, Sanz MN, Pehmøller C, Shum M, Marette A, Mounier R, Treebak JT, Wojtaszewski JFP, Viollet B, Lantier L. Kjøbsted R, et al. FASEB J. 2018 Apr;32(4):1741-1777. doi: 10.1096/fj.201700442R. Epub 2018 Jan 5. FASEB J. 2018. PMID: 29242278 Free PMC article. Review.

7

Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells.

Shum M, Houde VP, Bellemare V, Junges Moreira R, Bellmann K, St-Pierre P, Viollet B, Foretz M, Marette A. Shum M, et al. J Biol Chem. 2019 Aug 9;294(32):12250-12260. doi: 10.1074/jbc.RA119.008488. Epub 2019 Jun 26. J Biol Chem. 2019. PMID: 31243102 Free PMC article.

8

Insulin activates RSK (p90 ribosomal S6 kinase) to trigger a new negative feedback loop that regulates insulin signaling for glucose metabolism.

Smadja-Lamère N, Shum M, Déléris P, Roux PP, Abe J, Marette A. Smadja-Lamère N, et al. J Biol Chem. 2013 Oct 25;288(43):31165-76. doi: 10.1074/jbc.M113.474148. Epub 2013 Sep 13. J Biol Chem. 2013. PMID: 24036112 Free PMC article.

9

Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice.

Shum M, Bellmann K, St-Pierre P, Marette A. Shum M, et al. Diabetologia. 2016 Mar;59(3):592-603. doi: 10.1007/s00125-015-3839-6. Epub 2016 Jan 5. Diabetologia. 2016. PMID: 26733005

10

Loss of hepatic DEPTOR alters the metabolic transition to fasting.

Caron A, Mouchiroud M, Gautier N, Labbé SM, Villot R, Turcotte L, Secco B, Lamoureux G, Shum M, Gélinas Y, Marette A, Richard D, Sabatini DM, Laplante M. Caron A, et al. Mol Metab. 2017 Feb 17;6(5):447-458. doi: 10.1016/j.molmet.2017.02.005. eCollection 2017 May. Mol Metab. 2017. PMID: 28462079 Free PMC article.

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