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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Rådmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Förster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M. Friedmann Angeli JP, et al. Among authors: beck h. Nat Cell Biol. 2014 Dec;16(12):1180-91. doi: 10.1038/ncb3064. Epub 2014 Nov 17. Nat Cell Biol. 2014. PMID: 25402683 Free PMC article.
The role of thioredoxin reductases in brain development.
Soerensen J, Jakupoglu C, Beck H, Förster H, Schmidt J, Schmahl W, Schweizer U, Conrad M, Brielmeier M. Soerensen J, et al. Among authors: beck h. PLoS One. 2008 Mar 19;3(3):e1813. doi: 10.1371/journal.pone.0001813. PLoS One. 2008. PMID: 18350150 Free PMC article.
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.
Hellfritsch J, Kirsch J, Schneider M, Fluege T, Wortmann M, Frijhoff J, Dagnell M, Fey T, Esposito I, Kölle P, Pogoda K, Angeli JP, Ingold I, Kuhlencordt P, Östman A, Pohl U, Conrad M, Beck H. Hellfritsch J, et al. Among authors: beck h. Antioxid Redox Signal. 2015 Apr 10;22(11):938-50. doi: 10.1089/ars.2014.5889. Antioxid Redox Signal. 2015. PMID: 25647640 Free PMC article.
Endothelial Dysfunction, and A Prothrombotic, Proinflammatory Phenotype Is Caused by Loss of Mitochondrial Thioredoxin Reductase in Endothelium.
Kirsch J, Schneider H, Pagel JI, Rehberg M, Singer M, Hellfritsch J, Chillo O, Schubert KM, Qiu J, Pogoda K, Kameritsch P, Uhl B, Pircher J, Deindl E, Müller S, Kirchner T, Pohl U, Conrad M, Beck H. Kirsch J, et al. Among authors: beck h. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1891-9. doi: 10.1161/ATVBAHA.116.307843. Epub 2016 Jul 7. Arterioscler Thromb Vasc Biol. 2016. PMID: 27386940
The mitochondrial thioredoxin reductase system (TrxR2) in vascular endothelium controls peroxynitrite levels and tissue integrity.
Kameritsch P, Singer M, Nuernbergk C, Rios N, Reyes AM, Schmidt K, Kirsch J, Schneider H, Müller S, Pogoda K, Cui R, Kirchner T, de Wit C, Lange-Sperandio B, Pohl U, Conrad M, Radi R, Beck H. Kameritsch P, et al. Among authors: beck h. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e1921828118. doi: 10.1073/pnas.1921828118. Proc Natl Acad Sci U S A. 2021. PMID: 33579817 Free PMC article.
Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia.
Kupatt C, Horstkotte J, Vlastos GA, Pfosser A, Lebherz C, Semisch M, Thalgott M, Büttner K, Browarzyk C, Mages J, Hoffmann R, Deten A, Lamparter M, Müller F, Beck H, Büning H, Boekstegers P, Hatzopoulos AK. Kupatt C, et al. Among authors: beck h. FASEB J. 2005 Sep;19(11):1576-8. doi: 10.1096/fj.04-3282fje. Epub 2005 Jul 11. FASEB J. 2005. PMID: 16009705
1,492 results