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VEGF-targeted therapy stably modulates the glycolytic phenotype of tumor cells.
Curtarello M, Zulato E, Nardo G, Valtorta S, Guzzo G, Rossi E, Esposito G, Msaki A, Pastò A, Rasola A, Persano L, Ciccarese F, Bertorelle R, Todde S, Plebani M, Schroer H, Walenta S, Mueller-Klieser W, Amadori A, Moresco RM, Indraccolo S. Curtarello M, et al. Cancer Res. 2015 Jan 1;75(1):120-33. doi: 10.1158/0008-5472.CAN-13-2037. Epub 2014 Nov 7. Cancer Res. 2015. PMID: 25381153
Glycolytic phenotype and AMP kinase modify the pathologic response of tumor xenografts to VEGF neutralization.
Nardo G, Favaro E, Curtarello M, Moserle L, Zulato E, Persano L, Rossi E, Esposito G, Crescenzi M, Casanovas O, Sattler U, Mueller-Klieser W, Biesalski B, Thews O, Canese R, Iorio E, Zanovello P, Amadori A, Indraccolo S. Nardo G, et al. Among authors: curtarello m. Cancer Res. 2011 Jun 15;71(12):4214-25. doi: 10.1158/0008-5472.CAN-11-0242. Epub 2011 May 5. Cancer Res. 2011. PMID: 21546569 Free article.
Notch3 signalling promotes tumour growth in colorectal cancer.
Serafin V, Persano L, Moserle L, Esposito G, Ghisi M, Curtarello M, Bonanno L, Masiero M, Ribatti D, Stürzl M, Naschberger E, Croner RS, Jubb AM, Harris AL, Koeppen H, Amadori A, Indraccolo S. Serafin V, et al. Among authors: curtarello m. J Pathol. 2011 Aug;224(4):448-60. doi: 10.1002/path.2895. Epub 2011 May 19. J Pathol. 2011. PMID: 21598247
Metabolic effects of anti-angiogenic therapy in tumors.
Zulato E, Curtarello M, Nardo G, Indraccolo S. Zulato E, et al. Among authors: curtarello m. Biochimie. 2012 Apr;94(4):925-31. doi: 10.1016/j.biochi.2012.01.001. Epub 2012 Jan 11. Biochimie. 2012. PMID: 22245704 Review.
Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1.
Masgras I, Ciscato F, Brunati AM, Tibaldi E, Indraccolo S, Curtarello M, Chiara F, Cannino G, Papaleo E, Lambrughi M, Guzzo G, Gambalunga A, Pizzi M, Guzzardo V, Rugge M, Vuljan SE, Calabrese F, Bernardi P, Rasola A. Masgras I, et al. Among authors: curtarello m. Cell Rep. 2017 Jan 17;18(3):659-672. doi: 10.1016/j.celrep.2016.12.056. Cell Rep. 2017. PMID: 28099845 Free article.
LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation.
Zulato E, Ciccarese F, Agnusdei V, Pinazza M, Nardo G, Iorio E, Curtarello M, Silic-Benussi M, Rossi E, Venturoli C, Panieri E, Santoro MM, Di Paolo V, Quintieri L, Ciminale V, Indraccolo S. Zulato E, et al. Among authors: curtarello m. Biochem Pharmacol. 2018 Oct;156:479-490. doi: 10.1016/j.bcp.2018.09.019. Epub 2018 Sep 15. Biochem Pharmacol. 2018. PMID: 30222967
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