Jiao L - Search Results

1

Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.

Kong X, Chen L, Jiao L, Jiang X, Lian F, Lu J, Zhu K, Du D, Liu J, Ding H, Zhang N, Shen J, Zheng M, Chen K, Liu X, Jiang H, Luo C. Kong X, et al. Among authors: jiao l. J Med Chem. 2014 Nov 26;57(22):9512-21. doi: 10.1021/jm501230c. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25369470

2

Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2.

Jiao L, Liu X. Jiao L, et al. Science. 2015 Oct 16;350(6258):aac4383. doi: 10.1126/science.aac4383. Epub 2015 Oct 15. Science. 2015. PMID: 26472914 Free PMC article.

3

Structural analysis of an active fungal PRC2.

Jiao L, Liu X. Jiao L, et al. Nucleus. 2016 May 3;7(3):284-91. doi: 10.1080/19491034.2016.1183849. Epub 2016 May 17. Nucleus. 2016. PMID: 27187637 Free PMC article.

4

Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".

Jiao L, Liu X. Jiao L, et al. Science. 2016 Dec 23;354(6319):1543. doi: 10.1126/science.aaj2335. Science. 2016. PMID: 28008038 Free PMC article.

5

A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin.

Chen S, Jiao L, Liu X, Yang X, Liu X. Chen S, et al. Among authors: jiao l. Mol Cell. 2020 Mar 19;77(6):1265-1278.e7. doi: 10.1016/j.molcel.2019.12.019. Epub 2020 Jan 17. Mol Cell. 2020. PMID: 31959557 Free PMC article.

6

A partially disordered region connects gene repression and activation functions of EZH2.

Jiao L, Shubbar M, Yang X, Zhang Q, Chen S, Wu Q, Chen Z, Rizo J, Liu X. Jiao L, et al. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):16992-17002. doi: 10.1073/pnas.1914866117. Epub 2020 Jul 6. Proc Natl Acad Sci U S A. 2020. PMID: 32631994 Free PMC article.

7

Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.

Chen S, Jiao L, Shubbar M, Yang X, Liu X. Chen S, et al. Among authors: jiao l. Mol Cell. 2018 Mar 1;69(5):840-852.e5. doi: 10.1016/j.molcel.2018.01.039. Mol Cell. 2018. PMID: 29499137 Free PMC article.

8

Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.

Zhao L, Hua T, Crowley C, Ru H, Ni X, Shaw N, Jiao L, Ding W, Qu L, Hung LW, Huang W, Liu L, Ye K, Ouyang S, Cheng G, Liu ZJ. Zhao L, et al. Among authors: jiao l. Cell Res. 2014 Mar;24(3):344-58. doi: 10.1038/cr.2014.4. Epub 2014 Jan 10. Cell Res. 2014. PMID: 24407422 Free PMC article.

9

Mechanism of the Rpn13-induced activation of Uch37.

Jiao L, Ouyang S, Shaw N, Song G, Feng Y, Niu F, Qiu W, Zhu H, Hung LW, Zuo X, Eleonora Shtykova V, Zhu P, Dong YH, Xu R, Liu ZJ. Jiao L, et al. Protein Cell. 2014;5(8):616-30. doi: 10.1007/s13238-014-0046-z. Epub 2014 Apr 22. Protein Cell. 2014. PMID: 24752541 Free PMC article.

10

Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin.

Gu J, Feng Y, Feng X, Sun C, Lei L, Ding W, Niu F, Jiao L, Yang M, Li Y, Liu X, Song J, Cui Z, Han D, Du C, Yang Y, Ouyang S, Liu ZJ, Han W. Gu J, et al. Among authors: jiao l. PLoS Pathog. 2014 May 15;10(5):e1004109. doi: 10.1371/journal.ppat.1004109. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24831957 Free PMC article.

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