Yang F - Search Results

1

Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.

Yang F, Zhang T, Wu H, Yang Y, Liu N, Chen A, Li Q, Li J, Qin L, Jiang B, Wang X, Pang X, Yi Z, Liu M, Chen Y. Yang F, et al. Among authors: yang y. J Med Chem. 2014 Nov 26;57(22):9357-69. doi: 10.1021/jm5012148. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25360834

2

Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β signaling pathway.

Zheng C, Fang Y, Tong W, Li G, Wu H, Zhou W, Lin Q, Yang F, Yang Z, Wang P, Peng Y, Pang X, Yi Z, Luo J, Liu M, Chen Y. Zheng C, et al. Among authors: yang f, yang z. J Med Chem. 2014 Feb 13;57(3):600-12. doi: 10.1021/jm401117t. Epub 2014 Jan 27. J Med Chem. 2014. PMID: 24417479

3

Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents.

Wu J, Yu L, Yang F, Li J, Wang P, Zhou W, Qin L, Li Y, Luo J, Yi Z, Liu M, Chen Y. Wu J, et al. Among authors: yang f. Eur J Med Chem. 2014 Jun 10;80:340-51. doi: 10.1016/j.ejmech.2014.04.068. Epub 2014 Apr 24. Eur J Med Chem. 2014. PMID: 24794770

4

Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer.

Zhang T, Chen Y, Li J, Yang F, Wu H, Dai F, Hu M, Lu X, Peng Y, Liu M, Zhao Y, Yi Z. Zhang T, et al. Among authors: yang f. Neoplasia. 2014 Aug;16(8):665-77. doi: 10.1016/j.neo.2014.07.009. Neoplasia. 2014. PMID: 25220594 Free PMC article.

5

Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, by down-regulating EGFR expression.

Li J, Zhang T, Yang F, He Y, Dai F, Gao D, Chen Y, Liu M, Yi Z. Li J, et al. Among authors: yang f. Br J Pharmacol. 2015 Aug;172(15):3817-30. doi: 10.1111/bph.13165. Epub 2015 Jun 12. Br J Pharmacol. 2015. PMID: 25884486 Free PMC article.

6

A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.

Yang F, Peng S, Li Y, Su L, Peng Y, Wu J, Chen H, Liu M, Yi Z, Chen Y. Yang F, et al. Org Biomol Chem. 2016 Feb 7;14(5):1727-35. doi: 10.1039/c5ob02250a. Org Biomol Chem. 2016. PMID: 26732459

7

Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer.

Zhang T, Li J, Ma X, Yang Y, Sun W, Jin W, Wang L, He Y, Yang F, Yi Z, Hua Y, Liu M, Chen Y, Cai Z. Zhang T, et al. Among authors: yang f, yang y. EBioMedicine. 2018 May;31:276-286. doi: 10.1016/j.ebiom.2018.05.003. EBioMedicine. 2018. PMID: 29759486 Free PMC article.

8

Synthesis and biological evaluation of thiophene-based hydroxamate derivatives as HDACis with antitumor activities.

Yang F, Han L, Zhao N, Yang Y, Ge D, Zhang H, Chen Y. Yang F, et al. Among authors: yang y. Future Med Chem. 2020 Apr;12(8):655-672. doi: 10.4155/fmc-2019-0343. Epub 2020 Mar 23. Future Med Chem. 2020. PMID: 32202140

9

A novel synthetic small molecule YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling.

Liu Y, He Y, Yang F, Cong X, Wang J, Peng S, Gao D, Wang W, Lan L, Ying X, Liu M, Chen Y, Yi Z. Liu Y, et al. Among authors: yang f. Sci China Life Sci. 2017 Feb;60(2):202-214. doi: 10.1007/s11427-016-0369-6. Epub 2017 Feb 13. Sci China Life Sci. 2017. PMID: 28194552

10

A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer.

Zhang T, Li J, He Y, Yang F, Hao Y, Jin W, Wu J, Sun Z, Li Y, Chen Y, Yi Z, Liu M. Zhang T, et al. Among authors: yang f. Nat Commun. 2018 Sep 13;9(1):3726. doi: 10.1038/s41467-018-06179-0. Nat Commun. 2018. PMID: 30213946 Free PMC article.

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