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151 results

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Page 1
MiR-34a deficiency accelerates medulloblastoma formation in vivo.
Thor T, Künkele A, Pajtler KW, Wefers AK, Stephan H, Mestdagh P, Heukamp L, Hartmann W, Vandesompele J, Sadowski N, Becker L, Garrett L, Hölter SM, Horsch M, Calzada-Wack J, Klein-Rodewald T, Racz I, Zimmer A, Beckers J, Neff F, Klopstock T, De Antonellis P, Zollo M, Wurst W, Fuchs H, Gailus-Durner V, Schüller U, de Angelis MH, Eggert A, Schramm A, Schulte JH. Thor T, et al. Among authors: neff f. Int J Cancer. 2015 May 15;136(10):2293-303. doi: 10.1002/ijc.29294. Epub 2014 Nov 25. Int J Cancer. 2015. PMID: 25348795
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.
de Angelis MH, Nicholson G, Selloum M, White J, Morgan H, Ramirez-Solis R, Sorg T, Wells S, Fuchs H, Fray M, Adams DJ, Adams NC, Adler T, Aguilar-Pimentel A, Ali-Hadji D, Amann G, André P, Atkins S, Auburtin A, Ayadi A, Becker J, Becker L, Bedu E, Bekeredjian R, Birling MC, Blake A, Bottomley J, Bowl M, Brault V, Busch DH, Bussell JN, Calzada-Wack J, Cater H, Champy MF, Charles P, Chevalier C, Chiani F, Codner GF, Combe R, Cox R, Dalloneau E, Dierich A, Di Fenza A, Doe B, Duchon A, Eickelberg O, Esapa CT, El Fertak L, Feigel T, Emelyanova I, Estabel J, Favor J, Flenniken A, Gambadoro A, Garrett L, Gates H, Gerdin AK, Gkoutos G, Greenaway S, Glasl L, Goetz P, Da Cruz IG, Götz A, Graw J, Guimond A, Hans W, Hicks G, Hölter SM, Höfler H, Hancock JM, Hoehndorf R, Hough T, Houghton R, Hurt A, Ivandic B, Jacobs H, Jacquot S, Jones N, Karp NA, Katus HA, Kitchen S, Klein-Rodewald T, Klingenspor M, Klopstock T, Lalanne V, Leblanc S, Lengger C, le Marchand E, Ludwig T, Lux A, McKerlie C, Maier H, Mandel JL, Marschall S, Mark M, Melvin DG, Meziane H, Micklich K, Mittelhauser C, Monassier L, Moulaert D, Muller S, Naton B, Neff F, Nolan PM, Nutter LM, Ollert M, Pavlovic G, Pellegata NS, … See abstract for full author list ➔ de Angelis MH, et al. Among authors: neff f. Nat Genet. 2015 Sep;47(9):969-978. doi: 10.1038/ng.3360. Epub 2015 Jul 27. Nat Genet. 2015. PMID: 26214591 Free PMC article.
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.
Kaklamanos A, Rozman J, Roulis M, Karagianni N, Armaka M, Wu M, Brachthäuser L, Calzada-Wack J, Horsch M, Beckers J, Rathkolb B, Adler T, Neff F, Wolf E, Gailus-Durner V, Fuchs H, de Angelis MH, Kollias G. Kaklamanos A, et al. Among authors: neff f. Sci Rep. 2017 May 25;7(1):2397. doi: 10.1038/s41598-017-02581-8. Sci Rep. 2017. PMID: 28546545 Free PMC article.
Srgap3⁻/⁻ mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes.
Waltereit R, Leimer U, von Bohlen Und Halbach O, Panke J, Hölter SM, Garrett L, Wittig K, Schneider M, Schmitt C, Calzada-Wack J, Neff F, Becker L, Prehn C, Kutscherjawy S, Endris V, Bacon C, Fuchs H, Gailus-Durner V, Berger S, Schönig K, Adamski J, Klopstock T, Esposito I, Wurst W, de Angelis MH, Rappold G, Wieland T, Bartsch D. Waltereit R, et al. Among authors: neff f. FASEB J. 2012 Nov;26(11):4418-28. doi: 10.1096/fj.11-202317. Epub 2012 Jul 20. FASEB J. 2012. PMID: 22820399
Innovations in phenotyping of mouse models in the German Mouse Clinic.
Fuchs H, Gailus-Durner V, Neschen S, Adler T, Afonso LC, Aguilar-Pimentel JA, Becker L, Bohla A, Calzada-Wack J, Cohrs C, Dewert A, Fridrich B, Garrett L, Glasl L, Götz A, Hans W, Hölter SM, Horsch M, Hurt A, Janas E, Janik D, Kahle M, Kistler M, Klein-Rodewald T, Lengger C, Ludwig T, Maier H, Marschall S, Micklich K, Möller G, Naton B, Prehn C, Puk O, Rácz I, Räss M, Rathkolb B, Rozman J, Scheerer M, Schiller E, Schrewe A, Steinkamp R, Stöger C, Sun M, Szymczak W, Treise I, Vargas Panesso IL, Vernaleken AM, Willershäuser M, Wolff-Muscate A, Zeh R, Adamski J, Beckers J, Bekeredjian R, Busch DH, Eickelberg O, Favor J, Graw J, Höfler H, Höschen C, Katus H, Klingenspor M, Klopstock T, Neff F, Ollert M, Schulz H, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Hrabě de Angelis M. Fuchs H, et al. Among authors: neff f. Mamm Genome. 2012 Oct;23(9-10):611-22. doi: 10.1007/s00335-012-9415-1. Epub 2012 Aug 29. Mamm Genome. 2012. PMID: 22926221 Free PMC article.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.
Becker L, Kling E, Schiller E, Zeh R, Schrewe A, Hölter SM, Mossbrugger I, Calzada-Wack J, Strecker V, Wittig I, Dumitru I, Wenz T, Bender A, Aichler M, Janik D, Neff F, Walch A, Quintanilla-Fend L, Floss T, Bekeredjian R, Gailus-Durner V, Fuchs H, Wurst W, Meitinger T, Prokisch H, de Angelis MH, Klopstock T. Becker L, et al. Among authors: neff f. PLoS One. 2014 Dec 15;9(12):e114918. doi: 10.1371/journal.pone.0114918. eCollection 2014. PLoS One. 2014. PMID: 25506927 Free PMC article.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Stribl C, Samara A, Trümbach D, Peis R, Neumann M, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Rathkolb B, Wolf E, Beckers J, Horsch M, Neff F, Kremmer E, Koob S, Reichert AS, Hans W, Rozman J, Klingenspor M, Aichler M, Walch AK, Becker L, Klopstock T, Glasl L, Hölter SM, Wurst W, Floss T. Stribl C, et al. Among authors: neff f. J Biol Chem. 2014 Apr 11;289(15):10769-10784. doi: 10.1074/jbc.M113.515940. Epub 2014 Feb 10. J Biol Chem. 2014. PMID: 24515116 Free PMC article.
Generation of mice lacking DUF1220 protein domains: effects on fecundity and hyperactivity.
Keeney JG, O'Bleness MS, Anderson N, Davis JM, Arevalo N, Busquet N, Chick W, Rozman J, Hölter SM, Garrett L, Horsch M; German Mouse Clinic Consortium; Beckers J, Wurst W, Klingenspor M, Restrepo D, de Angelis MH, Sikela JM. Keeney JG, et al. Mamm Genome. 2015 Feb;26(1-2):33-42. doi: 10.1007/s00335-014-9545-8. Epub 2014 Oct 12. Mamm Genome. 2015. PMID: 25308000 Free PMC article.
151 results