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Discovery of the first histone deacetylase 6/8 dual inhibitors.
Olson DE, Wagner FF, Kaya T, Gale JP, Aidoud N, Davoine EL, Lazzaro F, Weïwer M, Zhang YL, Holson EB. Olson DE, et al. Among authors: holson eb. J Med Chem. 2013 Jun 13;56(11):4816-20. doi: 10.1021/jm400390r. Epub 2013 May 29. J Med Chem. 2013. PMID: 23672185
Small molecule inhibitors of zinc-dependent histone deacetylases.
Wagner FF, Weїwer M, Lewis MC, Holson EB. Wagner FF, et al. Among authors: holson eb. Neurotherapeutics. 2013 Oct;10(4):589-604. doi: 10.1007/s13311-013-0226-1. Neurotherapeutics. 2013. PMID: 24101253 Free PMC article. Review.
An unbiased approach to identify endogenous substrates of "histone" deacetylase 8.
Olson DE, Udeshi ND, Wolfson NA, Pitcairn CA, Sullivan ED, Jaffe JD, Svinkina T, Natoli T, Lu X, Paulk J, McCarren P, Wagner FF, Barker D, Howe E, Lazzaro F, Gale JP, Zhang YL, Subramanian A, Fierke CA, Carr SA, Holson EB. Olson DE, et al. Among authors: holson eb. ACS Chem Biol. 2014 Oct 17;9(10):2210-6. doi: 10.1021/cb500492r. Epub 2014 Aug 11. ACS Chem Biol. 2014. PMID: 25089360 Free PMC article.
Selective HDAC inhibition for the disruption of latent HIV-1 infection.
Barton KM, Archin NM, Keedy KS, Espeseth AS, Zhang YL, Gale J, Wagner FF, Holson EB, Margolis DM. Barton KM, et al. Among authors: holson eb. PLoS One. 2014 Aug 19;9(8):e102684. doi: 10.1371/journal.pone.0102684. eCollection 2014. PLoS One. 2014. PMID: 25136952 Free PMC article.
54 results