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Dietary iron restriction or iron chelation protects from diabetes and loss of beta-cell function in the obese (ob/ob lep-/-) mouse.
Cooksey RC, Jones D, Gabrielsen S, Huang J, Simcox JA, Luo B, Soesanto Y, Rienhoff H, Abel ED, McClain DA. Cooksey RC, et al. Among authors: simcox ja. Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1236-43. doi: 10.1152/ajpendo.00022.2010. Epub 2010 Mar 30. Am J Physiol Endocrinol Metab. 2010. PMID: 20354157 Free PMC article.
Adipocyte iron regulates adiponectin and insulin sensitivity.
Gabrielsen JS, Gao Y, Simcox JA, Huang J, Thorup D, Jones D, Cooksey RC, Gabrielsen D, Adams TD, Hunt SC, Hopkins PN, Cefalu WT, McClain DA. Gabrielsen JS, et al. Among authors: simcox ja. J Clin Invest. 2012 Oct;122(10):3529-40. doi: 10.1172/JCI44421. Epub 2012 Sep 10. J Clin Invest. 2012. PMID: 22996660 Free PMC article.
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism.
McClain DA, Abuelgasim KA, Nouraie M, Salomon-Andonie J, Niu X, Miasnikova G, Polyakova LA, Sergueeva A, Okhotin DJ, Cherqaoui R, Okhotin D, Cox JE, Swierczek S, Song J, Simon MC, Huang J, Simcox JA, Yoon D, Prchal JT, Gordeuk VR. McClain DA, et al. Among authors: simcox ja. J Mol Med (Berl). 2013 Jan;91(1):59-67. doi: 10.1007/s00109-012-0961-5. Epub 2012 Sep 27. J Mol Med (Berl). 2013. PMID: 23015148 Free PMC article.
Iron and diabetes risk.
Simcox JA, McClain DA. Simcox JA, et al. Cell Metab. 2013 Mar 5;17(3):329-41. doi: 10.1016/j.cmet.2013.02.007. Cell Metab. 2013. PMID: 23473030 Free PMC article. Review.
Adipocyte iron regulates leptin and food intake.
Gao Y, Li Z, Gabrielsen JS, Simcox JA, Lee SH, Jones D, Cooksey B, Stoddard G, Cefalu WT, McClain DA. Gao Y, et al. Among authors: simcox ja. J Clin Invest. 2015 Sep;125(9):3681-91. doi: 10.1172/JCI81860. Epub 2015 Aug 24. J Clin Invest. 2015. PMID: 26301810 Free PMC article.
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis.
Panic V, Pearson S, Banks J, Tippetts TS, Velasco-Silva JN, Lee S, Simcox J, Geoghegan G, Bensard CL, van Ry T, Holland WL, Summers SA, Cox J, Ducker GS, Rutter J, Villanueva CJ. Panic V, et al. Elife. 2020 Aug 14;9:e52558. doi: 10.7554/eLife.52558. Elife. 2020. PMID: 32795388 Free PMC article.
37 results